L-Tyrosine-15N
L-Tyrosine-15N (CAS: 35424-81-8) is an isotopically labelled derivative of the essential amino acid L-tyrosine, featuring a 15N atom substitution. With a molecular weight of 182.18 g/mol, this compound is primarily utilised in advanced research applications such as proteomics, biomolecular NMR, and mass spectrometry. Its specific isotopic labelling aids in tracking metabolic pathways and structural analysis of biomolecules.
Mass Spectrometry and Proteomics
L-Tyrosine-15N serves as a valuable internal standard or tracer in mass spectrometry-based proteomics. It helps in quantifying protein abundance and identifying post-translational modifications by providing a stable isotope-labelled reference.
Biomolecular NMR Spectroscopy
The 15N enrichment facilitates NMR studies of protein structure, dynamics, and interactions. It allows for specific signal assignment and analysis of biological macromolecules at an atomic level.
Metabolic Pathway Tracing
Researchers use L-Tyrosine-15N to investigate metabolic routes involving tyrosine and its derivatives. This helps in understanding cellular processes and drug metabolism.
| Molecular weight | 182.18 |
|---|---|
| Linear formula | 4-(OH)C6H4CH2CH(15NH2)CO2H |
| Optical activity | [α]25/D -12.0°, c = 1 in 1 M HCl |
| Melting point | >300 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Isotopic Purity | 98 atom % 15N |
|---|---|
| Mol Wt | mol wt 182.18 by atom % calculation |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Tyrosine-15N used for?
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L-Tyrosine-15N is primarily used in research applications such as mass spectrometry, proteomics, biomolecular NMR spectroscopy, and metabolic pathway tracing due to its specific isotopic labelling.
What are the CAS number and chemical formula for L-Tyrosine-15N?
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The CAS number for L-Tyrosine-15N is 35424-81-8, and its chemical formula is 4-(OH)C6H4CH2CH(15NH2)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Tyrosine-15N with an isotopic purity of 98 atom % 15N. This compound is suitable for research and laboratory use. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should L-Tyrosine-15N be handled safely?
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L-Tyrosine-15N is a Warning substance (GHS07) that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear a dust mask type N95 (US), eyeshields, and gloves, and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is L-Tyrosine-15N packed and exported?
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L-Tyrosine-15N is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions, adhering to international shipping regulations for chemicals.
How can I request a quote or sample of L-Tyrosine-15N?
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To request a quote or a sample of L-Tyrosine-15N, please contact our sales department through the Tech Serve Solutions website or by phone, providing your specific requirements.
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