L-Leucine-15N
L-Leucine-15N (CAS 59935-31-8) is an isotopically labeled amino acid with the linear formula (CH3)2CHCH2CH(15NH2)CO2H and a molecular weight of 132.17 g/mol. This compound is utilized in advanced research, particularly in areas requiring isotopic tracing. Its primary applications include biomolecular NMR, mass spectrometry, and proteomics studies, enabling detailed analysis of protein structures and metabolic pathways.
Biomolecular NMR Spectroscopy
L-Leucine-15N serves as a valuable tool in Nuclear Magnetic Resonance (NMR) spectroscopy for elucidating the three-dimensional structures and dynamics of proteins and other biomolecules. The incorporation of the 15N isotope allows for specific signal detection and spectral assignment.
Mass Spectrometry and Proteomics
In mass spectrometry-based proteomics, L-Leucine-15N is used for quantitative analysis and metabolic flux studies. Its presence as a stable isotope label facilitates accurate identification and quantification of proteins and peptides within complex biological samples.
Stable Isotope Labeling
As a stably isotope-labeled amino acid, it is employed in metabolic research to trace the fate of leucine within biological systems. This is crucial for understanding protein synthesis rates and metabolic pathways.
| Molecular weight | 132.17 |
|---|---|
| Linear formula | (CH3)2CHCH2CH(15NH2)CO2H |
| Optical activity | [α]25/D +14.5°, c = 2 in 5 M HCl |
| Melting point | >300 °C(lit.) |
| Mol Wt | mol wt 132.16 by atom % calculation |
|---|---|
| Mass Shift | M+1 |
| Isotopic Purity | 98 atom % 15N |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Leucine-15N used for?
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L-Leucine-15N is primarily used in advanced research applications such as biomolecular NMR spectroscopy, mass spectrometry, proteomics, and metabolic studies requiring stable isotope labeling for tracing and quantification.
What is the CAS number and formula for L-Leucine-15N?
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The CAS number for L-Leucine-15N is 59935-31-8, and its linear formula is (CH3)2CHCH2CH(15NH2)CO2H. The molecular weight is approximately 132.17 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Leucine-15N with a specified isotopic purity of 98 atom % 15N. It is supplied for research and technical purposes; TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How is L-Leucine-15N handled and stored?
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L-Leucine-15N has a melting point >300 °C and a WGK Germany rating of 1, indicating low hazard. Standard laboratory practices for handling fine chemicals should be followed. Store in a cool, dry place.
Is L-Leucine-15N exported or shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including L-Leucine-15N, and can accommodate international shipping requests.
How can I request a sample or quote for L-Leucine-15N?
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To request a sample or obtain a quote for L-Leucine-15N, please contact the Tech Serve Solutions sales department through our website or by phone.
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