Iodoacetic acid-1-13C
Iodoacetic acid-1-13C (CAS: 286367-80-4) is a deuterated organic acid with the formula ICH213CO2H and a molecular weight of 186.94 g/mol. This compound is a valuable tool in chemical synthesis and research, particularly in studies requiring isotopic labelling. Its unique isotopic composition allows for precise tracking and analysis in various biochemical and chemical processes, contributing to advancements in scientific understanding.
Isotopic Labeling Studies
Iodoacetic acid-1-13C is employed in research to introduce stable isotopes into molecules, enabling the tracing of metabolic pathways and reaction mechanisms. The 13C label allows for unambiguous detection using mass spectrometry or NMR spectroscopy.
Chemical Synthesis
As a synthetic reagent, this compound can be used in alkylation reactions where the resulting product needs to be isotopically labelled for analytical purposes. It serves as a building block for more complex labelled organic molecules.
Biochemical Research
It is utilised in biochemical investigations to study enzyme kinetics and protein modification. The selective alkylation of cysteine residues by iodoacetic acid, combined with isotopic labelling, aids in identifying and quantifying protein targets.
| Molecular weight | 186.94 |
|---|---|
| Linear formula | ICH213CO2H |
| Melting point | 77-79 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2923 6.1(8) / PGI |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,C |
| Risk statements (R) | 25-35 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 186.93 by atom % calculation |
|---|---|
| Isotopic Purity | 99 atom % 13C |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Iodoacetic acid-1-13C used for?
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Iodoacetic acid-1-13C is primarily used for isotopic labeling studies in chemical synthesis and biochemical research, enabling the tracking of molecules and mechanisms.
What are the CAS number and formula for Iodoacetic acid-1-13C?
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The CAS number for Iodoacetic acid-1-13C is 286367-80-4, and its formula is ICH213CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Iodoacetic acid-1-13C with an isotopic purity of 99 atom % 13C. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should I safely handle Iodoacetic acid-1-13C?
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Iodoacetic acid-1-13C is a dangerous substance that causes severe skin burns and eye damage and may be toxic if swallowed. Handle with extreme caution, wearing appropriate personal protective equipment including gloves, eye protection, and protective clothing. Ensure adequate ventilation.
Is Iodoacetic acid-1-13C a controlled substance?
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The provided data does not indicate that Iodoacetic acid-1-13C is a controlled substance.
How is Iodoacetic acid-1-13C shipped?
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Iodoacetic acid-1-13C is shipped under UN 2923, Hazard Class 6.1 (8), Packing Group I, indicating it is transported as a dangerous good requiring specialised handling.
How can I request a quote or sample?
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To request a quote or sample of Iodoacetic acid-1-13C, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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