HA-1077 dihydrochloride
HA-1077 dihydrochloride (CAS: 203911-27-7) is a white to off-white solid with the molecular formula C14H17N3O2S · 2HCl and a molecular weight of 364.29 g/mol. This compound is recognised as a modulator of calcium channels and plays a role in cell signalling pathways. It is primarily utilised in biological research for investigating cellular processes, particularly those involving ion channels and neuroscience.
- IUPAC
- 1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride,Fasudil dihydrochloride
- Synonyms
- 1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride

Calcium Channel Modulation Research
HA-1077 dihydrochloride serves as a valuable tool for researchers studying the function and modulation of calcium channels. Its specific action can help elucidate the role of these channels in various physiological and pathological processes.
Cell Signaling Pathway Investigations
This compound is employed in cell biology to investigate intricate cell signalling pathways. Researchers can use it to understand how extracellular signals are transmitted within cells, impacting cellular behaviour and responses.
Neuroscience Research Reagent
As a modulator of voltage-gated ion channels, HA-1077 dihydrochloride is applicable in neuroscience research. It aids in understanding neuronal function, excitability, and the mechanisms underlying neurological processes.
| Molecular weight | 364.29 |
|---|---|
| Empirical formula | C14H17N3O2S · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: >10 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is HA-1077 dihydrochloride used for?
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HA-1077 dihydrochloride is primarily used in biological research for investigating calcium channel modulation, cell signalling pathways, and as a reagent in neuroscience research related to voltage-gated ion channels.
What are the CAS number and formula for HA-1077 dihydrochloride?
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The CAS number for HA-1077 dihydrochloride is 203911-27-7, and its empirical formula is C14H17N3O2S · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies HA-1077 dihydrochloride with a purity of ≥98% (HPLC). This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations when handling HA-1077 dihydrochloride?
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When handling HA-1077 dihydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne particles are a concern. Note that this compound has a WGK Germany rating of 3, indicating a high degree of hazard.
How is HA-1077 dihydrochloride packed, shipped, and exported?
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HA-1077 dihydrochloride is typically supplied as a white to off-white solid. Tech Serve Solutions, as a global supplier, packs and exports chemicals in compliance with all relevant international shipping regulations to ensure safe and secure delivery worldwide.
How can I request a sample or quote for HA-1077 dihydrochloride?
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To request a sample or a quotation for HA-1077 dihydrochloride, please contact our sales department through the website or by calling our main office. Our team will be pleased to assist you with your requirements.
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