Glycine-13C2,15N
Glycine-13C2,15N (CAS: 211057-02-2), a doubly and singly labelled amino acid with the linear formula H₂¹⁵NCH₂¹³CO₂H and a molecular weight of 77.99 g/mol, is essential for isotopic tracing in biochemical and metabolic studies. It is frequently utilised in mass spectrometry, NMR spectroscopy, and proteomics research to track metabolic pathways and quantify protein abundance. This stable isotope-labelled compound offers unparalleled precision in analytical applications.
- IUPAC
- 13C and 15N Labeled glycine,Aminoacetic acid-13C2,15N,Aminoethanoic acid-13C2,15N
- Synonyms
- 13C2,15N-GlycineH215N13CH213CO2HAminoacetic acid-13C2,15NAminoethanoic acid-13C2,15N
Isotopic Labeling in Proteomics
Glycine-13C2,15N serves as a critical internal standard or tracer in quantitative proteomics workflows, including SILAC (Stable Isotope Labeling by Amino acids in Cell culture), enabling accurate measurement of protein expression changes.
NMR Spectroscopy Studies
The ¹³C and ¹⁵N labels facilitate detailed structural and dynamic studies of proteins and peptides using Nuclear Magnetic Resonance (NMR) spectroscopy, aiding in understanding molecular interactions and folding.
Metabolic Pathway Analysis
By incorporating this labelled glycine into biological systems, researchers can trace metabolic flux through various pathways, elucidating cellular processes and identifying key metabolic intermediates.
Mass Spectrometry Applications
The distinct mass shift (M+3) introduced by the ¹³C2 and ¹⁵N labels allows for precise detection and quantification of glycine and its metabolites using mass spectrometry techniques.
| Molecular weight | 78.05 |
|---|---|
| Linear formula | H215N13CH213CO2H |
| Melting point | 240 °C (dec.)(lit.) |
| Mol Wt | mol wt 77.99 by atom % calculation |
|---|---|
| Isotopic Purity | 99 atom % 13C98 atom % 15N |
| Mass Shift | M+3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycine-13C2,15N used for?
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Glycine-13C2,15N is used as a stable isotope-labelled compound for research applications, including isotopic tracing in metabolic studies, quantitative proteomics, NMR spectroscopy, and mass spectrometry.
What are the CAS number and formula for Glycine-13C2,15N?
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The CAS number for Glycine-13C2,15N is 211057-02-2, and its linear formula is H₂¹⁵NCH₂¹³CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Glycine-13C2,15N with 99 atom % ¹³C and 98 atom % ¹⁵N isotopic purity. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for Glycine-13C2,15N?
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Glycine-13C2,15N has a WGK Germany rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area, avoiding dust formation and contact with skin and eyes. Refer to the Safety Data Sheet for detailed handling information.
How is Glycine-13C2,15N packed, shipped, and exported?
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Tech Serve Solutions securely packs and ships its chemical products globally, adhering to all relevant regulations for the export of laboratory reagents and fine chemicals.
How can I request a sample or quote for Glycine-13C2,15N?
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To request a sample or quote for Glycine-13C2,15N, please contact our sales department through the website or by phone.
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