Glycerol-13C3
Glycerol-13C3 (CAS 63346-81-6) is a isotopically labeled compound with the linear formula (HO<sup>13</sup>CH<sub>2</sub>)<sub>2</sub><sup>13</sup>CHOH and a molecular weight of 95.07 g/mol. This glycerol derivative is specifically enriched with carbon-13 at three positions, making it invaluable for applications requiring precise mass or NMR tracking. It serves as a critical building block and internal standard in biochemical research, metabolic studies, and advanced analytical techniques like mass spectrometry.
- IUPAC
- 1,2,3-Propanetriol-13C3,13C Labeled glycerol,Glycerin-13C3
- Synonyms
- 1,2,3-Propanetriol-13C3Glycerin-13C313C Labeled glycerol

Mass Spectrometry Applications
Glycerol-13C3 is utilized as an internal standard in mass spectrometry for accurate quantification of glycerol or related metabolites. Its distinct mass shift allows for reliable differentiation from naturally abundant isotopes.
NMR Spectroscopy Studies
The 13C labeling enables detailed structural elucidation and metabolic flux analysis using Nuclear Magnetic Resonance (NMR) spectroscopy. It is particularly useful in biomolecular NMR for tracking metabolic pathways.
Metabolic Research
This labeled glycerol is employed in metabolic studies to trace carbon flow through biochemical pathways. Researchers use it to understand nutrient utilization and metabolic dynamics in biological systems.
Biochemical Synthesis
As a labeled building block, Glycerol-13C3 can be incorporated into more complex biomolecules, aiding in the study of their synthesis and function.
| Molecular weight | 95.07 |
|---|---|
| Linear formula | (HO13CH2)213CHOH |
| Boiling point | 182 °C(lit.) |
| Density | 1.302 g/mL at 25 °C |
| Refractive index | n20/D 1.474(lit.) |
| Melting point | 20 °C(lit.) |
| Flash point | 160 °C / 320 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 95.07 by atom % calculation |
|---|---|
| Isotopic Purity | 99 atom % 13C |
| Mass Shift | M+3 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glycerol-13C3 used for?
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Glycerol-13C3 is primarily used as a labeled compound in mass spectrometry and NMR spectroscopy for metabolic studies, flux analysis, and as an internal standard in quantitative analyses.
What is the CAS number and formula for Glycerol-13C3?
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The CAS number is 63346-81-6 and the linear formula is (HO<sup>13</sup>CH<sub>2</sub>)<sub>2</sub><sup>13</sup>CHOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Glycerol-13C3 with a minimum isotopic purity of 99 atom % 13C. This compound is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Glycerol-13C3 be handled?
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Glycerol-13C3 is a combustible liquid with a high flash point (160 °C / 320 °F). It requires handling away from ignition sources and in well-ventilated areas. Consult the Safety Data Sheet (SDS) for detailed handling and safety information. It has a WGK rating of 1.
Is Glycerol-13C3 a controlled substance?
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There is no indication in the provided data that Glycerol-13C3 is a controlled substance.
How is Glycerol-13C3 packed and shipped?
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Glycerol-13C3 is typically packed and shipped according to standard chemical transport regulations to ensure safe delivery. As a global supplier, Tech Serve Solutions adheres to international shipping standards for hazardous and non-hazardous materials.
How can I request a sample or quote for Glycerol-13C3?
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To request a sample or a quote, please contact our sales team through the Tech Serve Solutions website or by calling our dedicated inquiry line, referencing CAS number 63346-81-6.
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