Fmoc-D-Cys(Bzl)-OH
Fmoc-D-Cys(Bzl)-OH (CAS 252049-18-6) is a derivative of the D-enantiomer of cysteine, protected with an Fmoc group on the amine and a benzyl group on the thiol. This chiral building block, with the formula C25H23NO4S and a molecular weight of 433.52, is essential in solid-phase peptide synthesis. It enables the controlled incorporation of D-cysteine residues into peptide sequences, facilitating the study of peptide structure-activity relationships and the development of novel peptidomimetics.
- IUPAC
- Fmoc-S-benzyl-D-cysteine
Peptide Synthesis
Fmoc-D-Cys(Bzl)-OH is a key reagent in the Fmoc/tBu solid-phase peptide synthesis strategy. The benzyl protecting group on the sulfur atom provides robust protection during synthesis, while the N-terminal Fmoc group allows for facile deprotection and coupling steps.
Chemical Biology Research
This unnatural amino acid derivative is utilised in chemical biology to introduce specific modifications or structural constraints into peptides. Its incorporation can influence peptide folding, stability, and interactions with biological targets.
Drug Discovery
As a building block for peptidomimetics and modified peptides, Fmoc-D-Cys(Bzl)-OH aids in the discovery and development of new therapeutic agents. Its unique stereochemistry and protecting groups are valuable for creating peptides with enhanced pharmacological properties.
| Molecular weight | 433.52 |
|---|---|
| Empirical formula | C25H23NO4S |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Cys(Bzl)-OH used for?
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Fmoc-D-Cys(Bzl)-OH is primarily used as a protected amino acid derivative in solid-phase peptide synthesis, particularly for incorporating D-cysteine residues into peptide chains for research in peptide chemistry and chemical biology.
What are the CAS number and molecular formula of Fmoc-D-Cys(Bzl)-OH?
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The CAS number for Fmoc-D-Cys(Bzl)-OH is 252049-18-6, and its molecular formula is C25H23NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Cys(Bzl)-OH with an assay of ≥98.0% determined by HPLC. TSS does not represent this product as USP/BP/EP or any other pharmacopoeial grade.
How should Fmoc-D-Cys(Bzl)-OH be handled and stored?
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This compound requires careful handling. Personal protective equipment including eyeshields and gloves is recommended. A type N95 (US) or P1 (EN143) respirator filter should be used if airborne exposure is possible. Store at 2-8°C.
Is Fmoc-D-Cys(Bzl)-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Cys(Bzl)-OH is a controlled substance.
How are your chemicals packed and shipped?
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Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging for safe transport according to international regulations. Specific packing details can be provided upon request.
How can I request a sample or quote for Fmoc-D-Cys(Bzl)-OH?
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To request a sample or a quotation, please contact our sales team through the website or by telephone, providing your specific requirements and shipping details.
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