Dichlorodimethylsilane
Dichlorodimethylsilane (CAS: 75-78-5), with the linear formula (CH3)2SiCl2 and a molecular weight of 129.06 g/mol, is a versatile organosilicon compound. It is a colourless liquid known for its reactivity, particularly with water. Utilised extensively in chemical synthesis, it serves as a crucial reagent in the preparation of silicone polymers and as a derivatizing agent.
- IUPAC
- DMDCS,Dimethyldichlorosilane
- Synonyms
- DimethyldichlorosilaneDimethylsilane dichlorideDichlorodimethylsilaneDimethyldichlorsilaneDimethyl dichlorosilaneDimethyldichlorosilaneDimethyldichlorosilane

Silicone Polymer Synthesis
Dichlorodimethylsilane is a key monomer in the production of various silicone polymers, including polydimethylsiloxanes (PDMS). Its difunctional nature allows for polymer chain extension, forming the backbone of many silicone-based materials.
Protecting Group Reagent
In organic synthesis, this compound is employed as a derivatizing agent to protect hydroxyl and amine groups. This protection facilitates subsequent reactions by temporarily masking reactive functionalities.
Surface Modification
The reactivity of dichlorodimethylsilane allows for the modification of surfaces, particularly those with hydroxyl groups. This can alter surface properties such as hydrophobicity and adhesion.
Intermediate in Chemical Synthesis
As a reactive intermediate, it is used in the synthesis of other organosilicon compounds. Its controlled reactions enable the introduction of the dimethylsilyl moiety into complex molecules.
| Molecular weight | 129.06 |
|---|---|
| Linear formula | (CH3)2SiCl2 |
| Assay | ≥98.5% (GC) |
| Boiling point | 70 °C(lit.) |
| Density | 1.07 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.404(lit.) |
| Melting point | −76 °C(lit.) |



Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -5 °C / 23 °F |
| Transport (UN / ADR) | UN 1162 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-20/22-35-37 |
| Safety statements (S) | 7/9-16-26-36/37/39 |
| Supplemental hazards | Corrosive to the respiratory tract., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichlorodimethylsilane used for?
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Dichlorodimethylsilane is primarily used in chemical synthesis, particularly for the production of silicone polymers and as a protecting/derivatizing reagent in organic synthesis. It is also employed for surface modification.
What is the CAS number and formula for Dichlorodimethylsilane?
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The CAS number for Dichlorodimethylsilane is 75-78-5, and its linear formula is (CH3)2SiCl2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichlorodimethylsilane with a purity of ≥98.5% (GC). We do not represent this product as USP, BP, or EP grade.
How should Dichlorodimethylsilane be handled safely?
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Dichlorodimethylsilane is a flammable liquid and corrosive. It reacts violently with water, and its vapours are toxic and can irritate the respiratory tract. Handling requires appropriate personal protective equipment, including face shields, respirators, gloves, and goggles, in a well-ventilated area. Refer to the safety data sheet for full details.
Is Dichlorodimethylsilane a controlled substance?
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The provided data does not indicate that Dichlorodimethylsilane is a controlled substance.
How is Dichlorodimethylsilane packaged and shipped?
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Dichlorodimethylsilane is shipped as UN 1162, Hazard Class 8 (3), Packing Group II. Packaging is suitable for international export, adhering to transport regulations.
How can I request a quote or sample of Dichlorodimethylsilane?
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To request a quote or sample of Dichlorodimethylsilane, please contact our sales department through the website or by phone. Please specify the quantity required.
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