d-Desthiobiotin
d-Desthiobiotin (CAS: 533-48-2; Formula: C10H18N2O3) is a biotin analogue widely employed in biochemical research. With a molecular weight of 214.26 g/mol, it serves as a crucial reagent in affinity chromatography and protein labelling techniques. Its ability to bind to avidin and streptavidin makes it valuable for protein detection, isolation, and purification in molecular biology and proteomics.
- IUPAC
- 5-Methyl-2-oxo-4-imidazolidinehexanoic acid

Affinity Chromatography
d-Desthiobiotin is utilised as a ligand in affinity chromatography for the purification and isolation of proteins that bind to biotin or its analogues. This method is essential for enriching target proteins from complex biological mixtures.
Protein Labelling and Detection
It can be used for labelling proteins, enabling their subsequent detection and quantification. This is particularly useful in various assays and imaging techniques within molecular biology and proteomics research.
Molecular Biology Reagent
As a key reagent in molecular biology, d-Desthiobiotin aids in various experimental procedures, including protein purification strategies and diagnostic tool development.
| Molecular weight | 214.26 |
|---|---|
| Empirical formula | C10H18N2O3 |
| Assay | ≥98% (TLC) |
| Storage temperature | 2-8°C |
| Application | d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is d-Desthiobiotin used for?
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d-Desthiobiotin is primarily used in affinity chromatography and protein chromatography. It is valuable for protein labelling, detection, and isolation in fields like molecular biology and proteomics.
What are the CAS number and formula for d-Desthiobiotin?
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The CAS number for d-Desthiobiotin is 533-48-2, and its empirical formula (Hill notation) is C10H18N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies d-Desthiobiotin with an assay of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
How should d-Desthiobiotin be handled and stored?
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Handle d-Desthiobiotin with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at 2-8°C.
Is d-Desthiobiotin a controlled substance?
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The provided data does not indicate that d-Desthiobiotin is a controlled substance.
How is d-Desthiobiotin packed and exported?
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d-Desthiobiotin is packed and exported by Tech Serve Solutions according to industry standards to ensure product integrity during transit.
How can I request a sample or quote for d-Desthiobiotin?
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To request a sample or quote for d-Desthiobiotin, please contact the Tech Serve Solutions sales team through our website or direct inquiry channels.
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