Coelenterazine h
Coelenterazine h (CAS: 50909-86-9), with the molecular formula C26H21N3O2 and a molecular weight of 407.46 g/mol, is a bioluminescent substrate. It is primarily utilized in biochemical research for detecting and quantifying calcium ions due to its chemiluminescent properties upon interaction with calcium. This compound serves as a valuable tool in cell biology and neuroscience for studying intracellular calcium signaling pathways.
- IUPAC
- 2-Deoxycoelenterazine,CLZN-h
- Synonyms
- 2-DeoxycoelenterazineCLZN-h
Calcium Ion Detection
Coelenterazine h is widely employed as a chemiluminescent substrate for assays that measure intracellular calcium levels. Its light-emitting reaction, catalyzed by specific enzymes in the presence of calcium, allows for sensitive detection in biological samples.
Cell Signaling Research
This compound is instrumental in investigating calcium signaling pathways within cells. Researchers use it to monitor dynamic changes in cytosolic and organellar calcium concentrations, providing insights into cellular function and disease mechanisms.
Biotechnology and Diagnostics
Coelenterazine h finds application in the development of bioluminescent assays for diagnostic purposes and biotechnological tools. Its ability to produce light upon enzymatic activation makes it suitable for reporter gene assays and high-throughput screening.
Neuroscience Research
In neuroscience, Coelenterazine h aids in studying calcium dynamics in neuronal networks. Monitoring calcium influx and efflux is crucial for understanding synaptic transmission, neuronal excitability, and neurological disorders.
| Molecular weight | 407.46 |
|---|---|
| Empirical formula | C26H21N3O2 |
| Form | solid |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Coelenterazine h used for?
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Coelenterazine h is primarily used as a chemiluminescent substrate for the detection and quantification of calcium ions in biological research, particularly in studies of cell signaling, neuroscience, and biotechnology.
What is the CAS number and chemical formula for Coelenterazine h?
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The CAS number for Coelenterazine h is 50909-86-9, and its chemical formula is C26H21N3O2.
What grade and purity does Tech Serve Solutions supply for Coelenterazine h?
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Tech Serve Solutions supplies Coelenterazine h in a research grade. The exact purity is available on the Certificate of Analysis upon request. Tech Serve Solutions does not represent this product as USP, EP, BP, or pharmacopoeia grade.
How should Coelenterazine h be handled and stored?
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Coelenterazine h should be handled with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, as it may cause skin, eye, and respiratory irritation (H315-H319-H335). Store at -20°C in a tightly sealed container, away from moisture and light.
Is Coelenterazine h a controlled substance?
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The provided data does not indicate that Coelenterazine h is a controlled substance.
How are chemicals like Coelenterazine h packed, shipped, and exported?
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Tech Serve Solutions packs and ships chemicals in compliance with international regulations for hazardous materials. We are experienced in exporting fine chemicals globally to meet research and industrial needs.
How can I request a quote or sample for Coelenterazine h?
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To request a quote or sample for Coelenterazine h, please contact our sales department via the website or directly through the provided contact information, specifying the product name and CAS number.
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