Asenapine maleate
Asenapine maleate (CAS: 85650-56-2) is a white to off-white powder with a molecular weight of 401.84 g/mol. This compound functions as a serotonin (5-HT) and dopamine D2 receptor antagonist. Its primary application is in the treatment of schizophrenia and bipolar mania. Supplied by Tech Serve Solutions with an assay of ≥98% (HPLC), it is intended for research and analytical purposes.
- IUPAC
- (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12btetrahydro-1Hdibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate,Org 5222,trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate
- Synonyms
- (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioateOrg 5222trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate
Schizophrenia Treatment
Asenapine maleate is indicated for the management of schizophrenia. Its mechanism involves antagonism of serotonin and dopamine receptors, which are implicated in the pathophysiology of this disorder.
Bipolar Mania Management
This compound is also used in the treatment of manic or mixed episodes associated with bipolar I disorder. It helps to manage the acute symptoms of mania.
Neuroscience Research
As a selective antagonist for specific neurotransmitter receptors, asenapine maleate serves as a valuable tool in neuroscience research. It aids in studying receptor function and neurotransmission pathways.
| Molecular weight | 401.84 |
|---|---|
| Empirical formula | C17H16ClNO ·C4H4O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: ≥10 mg/mL |
| Storage temperature | 2-8°C |
| Application | Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania. |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36/37/38-50/53 |
| Safety statements (S) | 26-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Asenapine maleate used for?
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Asenapine maleate is used to treat schizophrenia and bipolar mania. It acts as a serotonin and dopamine receptor antagonist.
What is the CAS number and formula for Asenapine maleate?
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The CAS number for Asenapine maleate is 85650-56-2. The empirical formula (Hill notation) is C17H16ClNO ·C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Asenapine maleate with an assay of ≥98% (HPLC). This is a research grade material and TSS does not represent it as USP, BP, or EP grade.
How should Asenapine maleate be handled and stored?
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Asenapine maleate is classified as toxic if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation. It is also very toxic to aquatic life. Store at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.
Is Asenapine maleate a controlled substance?
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The provided data does not indicate that Asenapine maleate is a controlled substance. However, users should always verify local regulations.
How is Asenapine maleate packed, shipped, and exported?
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Asenapine maleate is shipped as a powder, often UN 2811, Class 6.1, Packing Group III, as per transport regulations. TSS is an experienced global exporter of fine chemicals.
How can I request a sample or quote for Asenapine maleate?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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