9-Deoxyforskolin from Coleus forskohlii
9-Deoxyforskolin (CAS: 84048-28-2, C22H34O6, MW: 394.50) is a diterpenoid derivative isolated from Coleus forskohlii. This compound serves as a valuable tool in cell biology and signaling research, particularly for investigating cellular processes influenced by cyclic AMP. Its applications extend to neuroscience and the study of drug transport mechanisms, including multi-drug resistance. Tech Serve Solutions supplies 9-Deoxyforskolin at an assay of ≥95%, making it suitable for laboratory and research purposes.
- IUPAC
- 7β-Acetoxy-1α,6β-dihydroxy-8,13-epoxy-labd-14-en-11-one
Cell Biology and Signaling Research
9-Deoxyforskolin is utilized to stimulate adenylyl cyclase activity, thereby increasing intracellular cyclic AMP (cAMP) levels. This makes it instrumental in studying cAMP-mediated cellular functions and signaling pathways.
Neuroscience Studies
This compound aids in the investigation of neuronal signaling and function. Its effects on cellular cAMP can be used to explore mechanisms related to neurotransmission and neurological disorders.
Drug Transport and Resistance Studies
As a modulator related to drug efflux pumps and transporters, 9-Deoxyforskolin is employed in research on multi-drug resistance (MDR) mechanisms and drug transport proteins.
Biochemical Assays
Its specific biochemical activity makes it a useful reagent in various in vitro assays aimed at understanding enzyme kinetics and cellular responses.
| Molecular weight | 394.50 |
|---|---|
| Empirical formula | C22H34O6 |
| Assay | ≥95% |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/22-36/37/38-40 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 9-Deoxyforskolin used for?
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9-Deoxyforskolin is used in research for cell biology, cell signaling, neuroscience, and studies involving drug efflux pumps and multi-drug resistance. It stimulates adenylyl cyclase and increases intracellular cyclic AMP levels.
What are the CAS number and formula for 9-Deoxyforskolin?
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The CAS number for 9-Deoxyforskolin is 84048-28-2, and its empirical formula is C22H34O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 9-Deoxyforskolin with an assay of ≥95%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 9-Deoxyforskolin be handled?
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9-Deoxyforskolin is a Warning substance. It is harmful if swallowed, causes skin irritation, serious eye irritation, harmful if inhaled, and may cause respiratory irritation. Wear appropriate personal protective equipment including eyeshields and gloves, and use in a well-ventilated area or with respiratory protection (N100/P3 recommended).
Is 9-Deoxyforskolin a controlled substance?
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The provided data does not indicate that 9-Deoxyforskolin (CAS: 84048-28-2) is a scheduled or controlled substance.
How is 9-Deoxyforskolin shipped and exported?
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9-Deoxyforskolin is typically stored at -20°C. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a quote or sample for 9-Deoxyforskolin?
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To request a quote or a sample of 9-Deoxyforskolin, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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