7-Ethoxycoumarin-3-carbonitrile
7-Ethoxycoumarin-3-carbonitrile (CAS 117620-77-6), molecular formula C12H9NO3, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- 3-Cyano-7-ethoxycoumarin
| Molecular weight | 215.20 |
|---|---|
| Empirical formula | C12H9NO3 |
| Assay | ≥99.0% (HPLC) |
| Solubility | DMSO: soluble |
| Application | This reagent is a fluorogenic substrate suitable for the continuous determination of cytochrome P450 mixed-function monooxygenases. The product of the reaction is the fluorescent compound 3-cyano-7-hydroxycoumarin (Product No. C 2737). This property has been utilized to determine the activity of CYP1A by measuring the rate of dealkylation of 3-Cyano-7-ethoxycoumarin to this fluorescent product 1. Fluorescence of 3-cyano-7-hydroxycoumarin occurs at neutral pH with excitation and emission at 408 and 450 nm, respectively 2. Fluorescent reaction product detection is at least 50-fold more sensitive than that of the product of alkyl resorufin oxidation because of greater rate of turnover of 3-Cyano-7-ethoxycoumarin 3,2. The ability to continuously monitor the enzyme reaction at pH 7 is derived from the lower pKa of the 3-cyano-7- hydroxycoumarin product compared to that for 7-ethoxycoumarin 4,5. 3-Cyano-7-ethoxycoumarin is a s |
| Suitability | suitable for fluorescence |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 324 nm; λem 414 nm in DMSO |
|---|
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Ethoxycoumarin-3-carbonitrile?
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7-Ethoxycoumarin-3-carbonitrile (CAS 117620-77-6), molecular formula C12H9NO3, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to USP, BP and EP standards.
What grades of 7-Ethoxycoumarin-3-carbonitrile does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7-Ethoxycoumarin-3-carbonitrile in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of 7-Ethoxycoumarin-3-carbonitrile?
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7-Ethoxycoumarin-3-carbonitrile has CAS number 117620-77-6 and molecular formula C12H9NO3. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for 7-Ethoxycoumarin-3-carbonitrile?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of 7-Ethoxycoumarin-3-carbonitrile ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should 7-Ethoxycoumarin-3-carbonitrile be stored?
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Store 7-Ethoxycoumarin-3-carbonitrile in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is 7-Ethoxycoumarin-3-carbonitrile used for?
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7-Ethoxycoumarin-3-carbonitrile is used in biochemicals & reagents applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for 7-Ethoxycoumarin-3-carbonitrile?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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