5HPP-33
5HPP-33 (CAS: 105624-86-0), with the molecular formula C20H21NO3 and a molecular weight of 323.39, is a chemical compound offered by Tech Serve Solutions. This white to off-white solid is primarily utilised in cell biology research, specifically within the fields of cell signalling, neuroscience, and the study of the cytoskeleton and extracellular matrix. Its role as a microtubule inhibitor makes it a valuable reagent for understanding cellular processes.
- IUPAC
- 2-[2,6-bis(1-Methylethyl)phenyl]-5-hydroxy-1H-isoindole-1,3(2H)-dione,5-Hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione
- Synonyms
- 2-[2,6-bis(1-Methylethyl)phenyl]-5-hydroxy-1H-isoindole-1,3(2H)-dione5-Hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione

Microtubule Inhibition Studies
5HPP-33 acts as a microtubule inhibitor, making it a key reagent for researchers investigating microtubule dynamics and their role in cellular structure and function. Its specific mechanism allows for precise manipulation of the cytoskeleton in experimental models.
Cell Signalling Research
Within cell signalling pathways, 5HPP-33 can be employed to elucidate the intricate mechanisms by which cells communicate. Its influence on the cytoskeleton can impact various downstream signalling cascades.
Neuroscience Applications
This compound finds application in neuroscience research, aiding the study of neuronal development, structure, and function. Researchers may use it to explore the role of microtubules in neuronal plasticity and maintenance.
Cytoskeleton and Extracellular Matrix Investigations
5HPP-33 is instrumental in studies focusing on the cytoskeleton and extracellular matrix. It allows for detailed examination of how these structural components interact and influence cellular behaviour.
| Molecular weight | 323.39 |
|---|---|
| Empirical formula | C20H21NO3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5HPP-33 used for?
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5HPP-33 is used in cell biology research, particularly in studies of cell signalling, neuroscience, and the cytoskeleton and extracellular matrix, functioning as a microtubule inhibitor.
What is the CAS number and formula for 5HPP-33?
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The CAS number for 5HPP-33 is 105624-86-0, and its molecular formula is C20H21NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5HPP-33 with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 5HPP-33 be handled and stored?
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5HPP-33 should be handled with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as hazardous to the aquatic environment (H410) and should be stored at 2-8°C.
Is 5HPP-33 available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5HPP-33. Please contact us for export inquiries.
How can I request a sample or quote for 5HPP-33?
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To request a sample or quote for 5HPP-33, please visit the Tech Serve Solutions website or contact our sales department directly.
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