5-(N-Methyl-N-isobutyl)amiloride

CAS 96861-65-3C11H18ClN7OBiochemicals & Reagents

5-(N-Methyl-N-isobutyl)amiloride (CAS: 96861-65-3) is a chemical compound with the formula C11H18ClN7O and a molecular weight of 299.76 g/mol. Supplied as a powder, it functions as a potent blocker of the Na+/H+ antiport. This compound is valuable for researchers studying early cellular responses to acidosis, particularly in the context of ion channel modulation.

IUPAC: MIA

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5-(N-Methyl-N-isobutyl)amiloride (C11H18ClN7O) — chemical structure, CAS 96861-65-3; Life Science, fine chemical supplied by Tech Serve Solutions

A to CAmiloride and DerivativesBioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Ion Channel Research

Serves as a potent blocker of the Na+/H+ antiport, enabling detailed investigation of ion transport mechanisms.

Cellular Acidosis Studies

Utilised to investigate the early cellular response mechanisms to acidosis in biological systems.

Biochemical Research

A useful reagent in biochemical studies, particularly for those involving enzyme inhibition and cell signalling pathways.

02 /Properties

Molecular weight	299.76
Empirical formula	C11H18ClN7O
Assay	≥98% (TLC)
Form	powder
Storage temperature	2-8°C
Application	5-(N-Methyl-N-isobutyl)amiloride is a potent blocker of the Na2/H+ antiport. 5-(N-Methyl-N-isobutyl)amiloride has been used to study early cellular response to acidosis.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

96861-65-3

MDL number

MFCD00078567

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-(N-Methyl-N-isobutyl)amiloride used for?

5-(N-Methyl-N-isobutyl)amiloride is used as a potent blocker of the Na+/H+ antiport and for studying early cellular responses to acidosis.

What is the CAS number and formula for 5-(N-Methyl-N-isobutyl)amiloride?

The CAS number is 96861-65-3 and the empirical formula is C11H18ClN7O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-(N-Methyl-N-isobutyl)amiloride with an assay of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.

How should 5-(N-Methyl-N-isobutyl)amiloride be handled?

Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet for detailed handling instructions.