5-Hydroxymethyl-2′-deoxyuridine

CAS 5116-24-5C10H14N2O6Biochemicals & Reagents

5-Hydroxymethyl-2′-deoxyuridine (CAS: 5116-24-5), with the empirical formula C10H14N2O6 and a molecular weight of 258.23 g/mol, is a vital nucleoside analog. It serves as a reliable marker for oxidative damage to nucleic acids, particularly DNA. This compound is also utilised in immunological research as an antigen for the development of specific anti-HMdUdr antibodies, aiding in the study of DNA repair mechanisms and related pathologies.

IUPAC: 5-HMdU,HMdUdr
Synonyms: 5-HMdUHMdUdr

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5-Hydroxymethyl-2′-deoxyuridine (C10H14N2O6) — chemical structure, CAS 5116-24-5; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleoside AnalogsNucleosidesNucleotidesOligonucleotides

01 /Applications

Biomarker for Oxidative DNA Damage

5-Hydroxymethyl-2′-deoxyuridine (HMdUdr) functions as a specific marker for oxidative damage incurred by DNA. Its presence in biological samples can indicate exposure to oxidative stress.

Antigen for Antibody Production

HMdUdr can be employed as an antigen to generate monoclonal or polyclonal antibodies. These antibodies are valuable tools for detecting and quantifying DNA damage in various research and diagnostic contexts.

Research in Nucleoside Chemistry

As a modified nucleoside, HMdUdr is of interest in synthetic organic chemistry and medicinal chemistry research for exploring nucleoside analog properties and potential therapeutic applications.

02 /Properties

Molecular weight	258.23
Empirical formula	C10H14N2O6
Assay	≥95% (HPLC)
Storage temperature	−20°C
Application	5-Hydroxymethyl-2′-deoxyuridine (HMdUdr) is a used as a marker for oxidative nucleic acid (DNA) damage. HMdUdr may be used as an antigen to create anti-HMdUdr antibodies.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

5116-24-5

MDL number

MFCD00047489

PubChem substance

24895526

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Hydroxymethyl-2′-deoxyuridine used for?

5-Hydroxymethyl-2′-deoxyuridine (HMdUdr) is used as a marker for oxidative nucleic acid (DNA) damage and as an antigen to create anti-HMdUdr antibodies.

What is the CAS number and formula for 5-Hydroxymethyl-2′-deoxyuridine?

The CAS number for 5-Hydroxymethyl-2′-deoxyuridine is 5116-24-5, and its empirical formula is C10H14N2O6.

What grade and purity does Tech Serve Solutions supply for 5-Hydroxymethyl-2′-deoxyuridine?

Tech Serve Solutions supplies 5-Hydroxymethyl-2′-deoxyuridine with a purity of ≥95% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should 5-Hydroxymethyl-2′-deoxyuridine be handled?

Handling of 5-Hydroxymethyl-2′-deoxyuridine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.

How is 5-Hydroxymethyl-2′-deoxyuridine packed, shipped, and exported?

5-Hydroxymethyl-2′-deoxyuridine is typically stored at -20°C. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping and customs regulations for hazardous materials.

How can I request a sample or quote for 5-Hydroxymethyl-2′-deoxyuridine?

To request a sample or obtain a quote for 5-Hydroxymethyl-2′-deoxyuridine, please contact our sales department via the website or email, providing your specific requirements.