5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt

CAS 103226-10-4C9H12FN2O8PBiochemicals & Reagents

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (CAS: 103226-10-4), with the molecular formula C9H12FN2O8P and a molecular weight of 326.17, is a crucial nucleotide analogue. It is primarily utilised in biochemical research for its role in studying thymidylate synthase (TS) activity and function. This compound serves as a key reagent in investigations related to enzyme mechanisms and the development of therapeutic strategies.

IUPAC: FdUMP

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5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (C9H12FN2O8P) — chemical structure, CAS 103226-10-4; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsNucleosidesNucleotidesOligonucleotidesNucleotide Analogs

01 /Applications

Thymidylate Synthase (TS) Studies

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt is extensively employed in research focused on the activity and mechanisms of thymidylate synthase (TS). Its interaction with TS is fundamental to understanding nucleotide metabolism and related enzymatic processes.

Biochemical Research Reagent

As a nucleotide analogue, this compound serves as a valuable reagent in various biochemical investigations. It aids in probing enzyme kinetics, reaction pathways, and the effects of nucleotide variations in biological systems.

Enzyme Inhibition Research

FdUMP is known to be a potent inhibitor of thymidylate synthase. Therefore, it is used to study enzyme inhibition mechanisms, which is critical for the design of targeted therapeutics, particularly in oncology.

02 /Properties

Molecular weight	326.17
Empirical formula	C9H12FN2O8P
Assay	~85%
Storage temperature	−20°C
Application	5-Fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) is used extensively in studies on the activity and function of thymidylate synthase (TS).

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22-40
Safety statements (S)	22-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

103226-10-4

MDL number

MFCD00057409

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt used for?

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is primarily used in biochemical research to study the activity and function of thymidylate synthase (TS).

What are the CAS number and molecular formula for this compound?

The CAS number is 103226-10-4, and the molecular formula is C9H12FN2O8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt with an assay of approximately 85%. This product is intended for research purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.

How should 5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt be handled safely?

This compound is classified as harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332) and is suspected of causing cancer (H351). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 US, P1/P3 EN143), should be used. Handle in a well-ventilated area.

Is this product suitable for export?

Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including 5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt.

How can I request a sample or quote?

To request a sample or a quote for 5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt, please contact our sales team through the website or by phone.