5-Ethyluracil
5-Ethyluracil (CAS 4212-49-1), with the molecular formula C6H8N2O2 and a molecular weight of 140.14 g/mol, is a pyrimidine derivative. This compound is primarily utilised in biochemical research and as a building block in the synthesis of nucleoside analogs. It plays a role in studies related to nucleic acid chemistry and is a valuable reagent for scientific investigation.
- IUPAC
- 2,4-Dihydroxy-5-ethylpyrimidine,Homothymine
- Synonyms
- Homothymine2,4-Dihydroxy-5-ethylpyrimidine

Biochemical Research
5-Ethyluracil serves as a reagent in various biochemical studies, particularly those involving nucleic acid metabolism and synthesis. Its structural similarity to natural pyrimidines makes it useful for investigating enzyme mechanisms and cellular processes.
Nucleoside Analog Synthesis
This compound is employed as a precursor in the synthesis of modified nucleosides and nucleoside analogs. These analogs can have applications in antiviral or anticancer research, acting as chain terminators or inhibitors of specific enzymes.
Organic Synthesis Intermediate
As a heterocyclic compound, 5-Ethyluracil can be utilised as an intermediate in broader organic synthesis pathways. Its functional groups allow for further chemical modifications to create more complex molecules.
| Molecular weight | 140.14 |
|---|---|
| Empirical formula | C6H8N2O2 |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Ethyluracil used for?
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5-Ethyluracil is used in biochemical research and as an intermediate for synthesising nucleoside analogs.
What is the CAS number and formula for 5-Ethyluracil?
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The CAS number is 4212-49-1 and the empirical formula is C6H8N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Ethyluracil typically as a research-grade chemical. The exact assay and purity will be detailed on the Certificate of Analysis provided with each batch. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 5-Ethyluracil be handled?
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Handle 5-Ethyluracil with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation, as it may cause skin irritation, eye irritation, and respiratory irritation (H315, H319, H335).
Is 5-Ethyluracil a controlled substance?
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The provided data does not indicate that 5-Ethyluracil is a controlled substance.
How is 5-Ethyluracil packed and shipped?
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5-Ethyluracil is carefully packed according to industry standards for chemical reagents and can be exported globally by Tech Serve Solutions.
How can I request a quote or sample for 5-Ethyluracil?
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Please contact our sales team directly through our website or by phone to request a quote or a sample of 5-Ethyluracil.
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