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4-Trifluoromethylumbelliferyl glucuronide potassium salt

CAS 143547-78-8C16H12F3O9KBiochemicals & Reagents

4-Trifluoromethylumbelliferyl glucuronide potassium salt (CAS: 143547-78-8) is a fluorogenic substrate with the molecular formula C16H12F3O9K and a molecular weight of 444.35. This compound is primarily utilised in biochemical research and molecular biology. It serves as a sensitive tool for detecting glucuronidase enzyme activity, making it valuable in various enzymatic assays and studies related to glycobiology and post-translational modifications. Its fluorogenic nature allows for quantitative analysis.

IUPAC
4-Trifluoromethyl-7-hydroxycoumarin glucuronide
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4-Trifluoromethylumbelliferyl glucuronide potassium salt (C16H12F3O9K) — chemical structure, CAS 143547-78-8; Life Science, fine chemical supplied by Tech Serve Solutions
ActivityBiochemicals and ReagentsEnzyme SubstratesEnzymesInhibitorsand SubstratesFluorogenicGlucuronideGlycobiologyInhibitors and Substrates
01 /Applications

Enzyme Activity Assays

This compound acts as a fluorogenic substrate for the enzyme glucuronidase. Upon enzymatic cleavage, it releases a fluorescent product, allowing for sensitive detection and quantification of enzyme activity in various biological samples.

Biochemical Research

It is employed in fundamental research concerning glycobiology, post-translational modifications, and proteomics. Researchers utilise it to study the function and regulation of glucuronidases in cellular processes.

Molecular Biology Applications

The substrate is valuable in molecular biology for applications requiring the detection of glucuronidase activity, such as in reporter gene assays or for monitoring enzyme expression levels.

02 /Properties
Molecular weight444.35
Linear formulaC16H12F3O9K
Assay≥98% (TLC)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
143547-78-8
MDL number
MFCD00132981
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Trifluoromethylumbelliferyl glucuronide potassium salt used for?

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4-Trifluoromethylumbelliferyl glucuronide potassium salt is primarily used as a fluorogenic substrate for detecting and quantifying glucuronidase enzyme activity in biochemical and molecular biology research.

What is the CAS number and chemical formula?

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The CAS number is 143547-78-8, and the chemical formula is C16H12F3O9K.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.

What safety precautions should be taken when handling this chemical?

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When handling, wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended. This compound has a WGK rating of 3 in Germany, indicating it is hazardous to water.

How is this chemical typically packed and shipped?

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This chemical is carefully packed to maintain its integrity during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.

How can I request a quote or sample?

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To request a quote or sample, please contact our sales department through the website or by calling our customer service line.

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