4-Fluoro-2-(trifluoromethyl)benzyl bromide
4-Fluoro-2-(trifluoromethyl)benzyl bromide (CAS: 206860-48-2), with the molecular formula FC6H3(CF3)CH2Br and a molecular weight of 257.02 g/mol, is a fluorinated aromatic compound. It serves as a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals due to the presence of reactive benzyl bromide and electron-withdrawing trifluoromethyl groups. This compound is essential for introducing fluorinated moieties into complex molecular structures.
- IUPAC
- 1-(Bromomethyl)-4-fluoro-2-(trifluoromethyl)benzene
- Synonyms
- 1-(Bromomethyl)-4-fluoro-2-(trifluoromethyl)benzene
Pharmaceutical Intermediate
This compound is utilised in the synthesis of novel pharmaceutical agents. Its unique fluorinated structure can impart desirable properties such as increased metabolic stability and lipophilicity to drug candidates.
Agrochemical Development
It acts as a key intermediate in the creation of advanced agrochemicals, including herbicides and insecticides. The trifluoromethyl and fluoro substituents can enhance the efficacy and persistence of these agricultural products.
Material Science Research
The compound finds application in the development of specialised materials, where its fluorinated nature can contribute to unique physical and chemical properties.
Organic Synthesis Building Block
As a versatile building block, it facilitates the introduction of the 4-fluoro-2-(trifluoromethyl)benzyl group into various organic molecules for diverse research and development purposes.
| Molecular weight | 257.02 |
|---|---|
| Linear formula | FC6H3(CF3)CH2Br |
| Assay | 98% |
| Boiling point | 141 °C(lit.) |
| Density | 1.665 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.482(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 2927 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-2-(trifluoromethyl)benzyl bromide used for?
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4-Fluoro-2-(trifluoromethyl)benzyl bromide is primarily used as a building block in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and novel materials due to its reactive benzyl bromide moiety and electron-withdrawing fluorinated substituents.
What are the CAS number and chemical formula?
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The CAS number is 206860-48-2, and the linear chemical formula is FC6H3(CF3)CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum assay of 98%. It is supplied as a research or technical grade chemical and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety concerns when handling this chemical?
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This compound is classified as corrosive, indicated by GHS hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including full-face respirators, gloves, and eye protection, must be worn. Handling should be conducted in a well-ventilated area or fume hood.
How is this chemical typically packed, shipped, and exported?
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This chemical is packed according to UN 2927 regulations for corrosive and toxic substances (Class 6.1, PG 2). TSS, as a specialist global supplier, handles the export of this product, adhering to all relevant international shipping and safety regulations.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department via the website or designated contact channels, providing the product name and CAS number.
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