4-Bromo-2-fluoroanisole
4-Bromo-2-fluoroanisole (CAS: 2357-52-0), with the molecular formula BrC6H3(F)OCH3 and a molecular weight of 205.02 g/mol, is a key organic building block. This fluorinated aromatic compound serves as a valuable intermediate in various chemical synthesis pathways, particularly in the development of advanced materials like liquid crystals and complex organic molecules. Its specific structure allows for targeted functionalization in research and industrial applications.
- IUPAC
- 4-Bromo-2-fluoro-1-methoxybenzene
Synthesis of Polycyclic Aromatic Compounds
This compound has been utilized in the synthesis of specific naphthaldehyde derivatives, such as 7-fluoro-6-methoxy-1-methyl-2-naphthaldehyde and 5,7-difluoro-6-methoxy-1-methyl-2-naphthaldehyde. These complex molecules are often precursors in the development of novel organic materials.
Development of Liquid Crystals
4-Bromo-2-fluoroanisole is employed in the synthesis of liquid crystal materials. Specifically, it has been used to create liquid crystals with a terminal difluoromethoxy group and a phenylbicyclohexane backbone, important for display technologies.
Precursor for Advanced Organic Structures
It serves as a building block for the creation of extended conjugated systems, such as 1,4-bis[(3′-fluoro-4′-n alkoxyphenyl)ethynyl]benzenes. These structures are investigated for their electronic and optical properties.
| Molecular weight | 205.02 |
|---|---|
| Linear formula | BrC6H3(F)OCH3 |
| Assay | 97% |
| Boiling point | 84 °C/7 mmHg(lit.) |
| Density | 1.59 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.545(lit.) |
| Application | 4-Bromo-2-fluoroanisole has been used in the synthesis of:• 1,4-bis[(3′-fluoro-4′-n alkoxyphenyl)ethynyl]benzenes with n=1-121• 7-fluoro-6-methoxy-1-methyl-2-naphthaldehyde2• 5,7-difluoro-6-methoxy-1-methyl-2-naphthaldehyde2• liquid crystals with terminal difluoromethoxy group and backbone of phenylbicyclohexane3 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-fluoroanisole used for?
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4-Bromo-2-fluoroanisole is used as a building block in organic synthesis, particularly in the preparation of fluorinated aromatic compounds, liquid crystals, and complex organic molecules for research and development.
What are the CAS number and molecular formula for 4-Bromo-2-fluoroanisole?
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The CAS number is 2357-52-0, and the molecular formula is BrC6H3(F)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-fluoroanisole with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Bromo-2-fluoroanisole be handled safely?
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4-Bromo-2-fluoroanisole is classified with Warning signal word, and hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment includes eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is 4-Bromo-2-fluoroanisole available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Bromo-2-fluoroanisole.
How can I request a quote or sample for 4-Bromo-2-fluoroanisole?
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You can request a quote or sample by contacting our sales department through the website or by calling us directly.
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