3,5-Difluoro-4-formylbenzonitrile
3,5-Difluoro-4-formylbenzonitrile (CAS: 467442-15-5) is a fluorinated aromatic aldehyde with the molecular formula C8H3F2NO and a molecular weight of 167.11 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the introduction of difluorobenzonitrile moieties into more complex molecules. Its reactive aldehyde group and the presence of two fluorine atoms on the phenyl ring make it a versatile intermediate for the development of novel chemical entities, pharmaceuticals, and materials.
- Synonyms
- C8H3F2NO

Organic Synthesis Intermediate
Utilised as a key building block in multi-step organic synthesis pathways. Its functional groups allow for various chemical transformations, making it useful for constructing complex molecular architectures.
Pharmaceutical Research
A valuable intermediate in the synthesis of potential pharmaceutical candidates. Fluorinated compounds are often explored for their enhanced metabolic stability and binding properties in drug discovery.
Materials Science
Can be employed in the development of novel organic materials, leveraging the electronic properties influenced by the fluorine substituents and the cyano group.
Agrochemical Development
Serves as a precursor in the synthesis of new agrochemical compounds, where fluorinated aromatics can impart specific biological activities.
| Molecular weight | 167.11 |
|---|---|
| Empirical formula | C8H3F2NO |
| Assay | 97% |
| Melting point | 97-101 °C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluoro-4-formylbenzonitrile used for?
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3,5-Difluoro-4-formylbenzonitrile is primarily used as a versatile intermediate and building block in organic synthesis, particularly for creating fluorinated compounds relevant to pharmaceutical research, materials science, and agrochemical development.
What is the CAS number and formula for 3,5-Difluoro-4-formylbenzonitrile?
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The CAS number for 3,5-Difluoro-4-formylbenzonitrile is 467442-15-5, and its empirical formula is C8H3F2NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Difluoro-4-formylbenzonitrile with an assay of 97%. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, or EP grade.
How should 3,5-Difluoro-4-formylbenzonitrile be handled safely?
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This compound is a Warning substance, harmful if swallowed, in contact with skin, or if inhaled. It causes skin irritation, serious eye irritation, and may cause respiratory irritation. Use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation, avoid breathing dust, and wear protective clothing.
Does Tech Serve Solutions export 3,5-Difluoro-4-formylbenzonitrile?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3,5-Difluoro-4-formylbenzonitrile.
How can I request a quote or sample?
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To request a quote or sample of 3,5-Difluoro-4-formylbenzonitrile, please contact our sales department via the website or by phone.
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