2′-O-Methylcytidine
2′-O-Methylcytidine (CAS: 2140-72-9) is a modified nucleoside with the empirical formula C10H15N3O5 and a molecular weight of 257.24 g/mol. It is an analogue of cytidine where the 2'-hydroxyl group of the ribose sugar is methylated. This modification impacts its biochemical properties, making it a valuable tool in molecular biology research and the synthesis of modified oligonucleotides.
Oligonucleotide Synthesis
2′-O-Methylcytidine serves as a building block for the synthesis of modified oligonucleotides, which can exhibit altered stability, binding affinity, and nuclease resistance compared to unmodified sequences.
Biochemical Research
It is utilised in various biochemical studies investigating the structure-function relationships of nucleic acids and the role of nucleoside modifications in biological processes.
Nucleoside Analog Development
As a nucleoside analog, it may be explored in the development of novel therapeutic agents or diagnostic tools requiring specific chemical properties.
| Molecular weight | 257.24 |
|---|---|
| Empirical formula | C10H15N3O5 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-O-Methylcytidine used for?
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2′-O-Methylcytidine is primarily used in the synthesis of modified oligonucleotides and in biochemical research to study nucleic acid structure and function.
What are the CAS number and formula for 2′-O-Methylcytidine?
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The CAS number is 2140-72-9 and the empirical formula is C10H15N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-O-Methylcytidine typically as a research-grade chemical. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or for nutraceutical/food use.
How should 2′-O-Methylcytidine be handled?
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Handle 2′-O-Methylcytidine with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 2′-O-Methylcytidine packaged and shipped?
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2′-O-Methylcytidine is stored at −20°C. It is carefully packaged for safe transport and can be exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2′-O-Methylcytidine?
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To request a sample or a quotation for 2′-O-Methylcytidine, please contact our sales department via the website or by phone, providing your specific requirements.
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