2-Chloro-6-(trifluoromethyl)phenyl isocyanate
2-Chloro-6-(trifluoromethyl)phenyl isocyanate (CAS: 16583-76-9, Formula: ClC6H3(CF3)NCO) is a versatile organic compound with a molecular weight of 221.56 g/mol. Possessing a reactive isocyanate group and a trifluoromethyl substituent, it serves as a key building block in organic synthesis. This compound is primarily utilised in the chemical industry for the development of complex molecules and specialised materials, functioning as an intermediate in various synthetic pathways.
Organic Synthesis Intermediate
Serves as a crucial intermediate in the synthesis of complex organic molecules. Its reactive isocyanate functionality allows for derivatisation into ureas, carbamates, and other nitrogen-containing compounds.
Pharmaceutical Research
Utilised in the preparation of novel pharmaceutical compounds. The trifluoromethyl group can enhance lipophilicity and metabolic stability of target drug candidates.
Material Science
Employed in the development of speciality polymers and materials where its unique structural features can impart specific properties.
| Molecular weight | 221.56 |
|---|---|
| Linear formula | ClC6H3(CF3)NCO |
| Assay | 97% |
| Boiling point | 206 °C(lit.) |
| Density | 1.489 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.498(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42/43 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-(trifluoromethyl)phenyl isocyanate used for?
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2-Chloro-6-(trifluoromethyl)phenyl isocyanate is used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and material science for the development of complex molecules and speciality materials.
What are the CAS number and formula for 2-Chloro-6-(trifluoromethyl)phenyl isocyanate?
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The CAS number is 16583-76-9, and the molecular formula is ClC6H3(CF3)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-6-(trifluoromethyl)phenyl isocyanate with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Chloro-6-(trifluoromethyl)phenyl isocyanate be handled safely?
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This compound is hazardous and requires careful handling. It is classified with GHS07 and GHS08 symbols, indicating danger. Hazards include H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Consult the safety data sheet for comprehensive guidance.
How is 2-Chloro-6-(trifluoromethyl)phenyl isocyanate packed, shipped, and exported?
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Tech Serve Solutions carefully packs and prepares 2-Chloro-6-(trifluoromethyl)phenyl isocyanate for secure domestic and international shipment, adhering to all relevant regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloro-6-(trifluoromethyl)phenyl isocyanate, please contact our sales team through the website or by phone.
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