2-Butenylmagnesium chloride solution
2-Butenylmagnesium chloride solution (CAS 22649-70-3), with the linear formula CH3CH=CHCH2MgCl and a molecular weight of 114.86 g/mol, is a vital organometallic reagent. Supplied as a 0.5 M solution in Tetrahydrofuran (THF), it serves as a potent nucleophile in organic synthesis. This compound is primarily employed in the formation of carbon-carbon bonds, facilitating the construction of more complex molecular architectures in research and development.

Carbon-Carbon Bond Formation
As a Grignard reagent, 2-Butenylmagnesium chloride solution is instrumental in nucleophilic addition reactions. It efficiently adds to electrophilic carbon centers such as aldehydes, ketones, esters, and epoxides, enabling the synthesis of substituted alkenes and alcohols.
Organometallic Synthesis
This compound is a key building block in organometallic chemistry. Its utility lies in introducing the 2-butenyl group into organic molecules, a common motif in natural products and pharmaceuticals.
Research and Development
Utilised extensively in academic and industrial research laboratories for the development of novel synthetic methodologies and the exploration of new chemical entities. Its predictable reactivity makes it a reliable tool for synthetic chemists.
| Molecular weight | 114.86 |
|---|---|
| Linear formula | CH3CH=CHCH2MgCl |
| Density | 0.921 g/mL at 25 °C |
| Concentration | 0.5 M in THF |



Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 14/15-19-20/21/22-34-37-40 |
| Safety statements (S) | 26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Butenylmagnesium chloride solution used for?
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2-Butenylmagnesium chloride solution is primarily used for carbon-carbon bond formation through nucleophilic addition reactions in organic synthesis and organometallic chemistry research.
What is the CAS number and chemical formula for 2-Butenylmagnesium chloride solution?
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The CAS number is 22649-70-3, and the linear chemical formula is CH3CH=CHCH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Butenylmagnesium chloride solution at a concentration of 0.5 M in THF. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
How should 2-Butenylmagnesium chloride solution be handled safely?
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Handling requires extreme caution due to its corrosive nature, toxicity upon inhalation and ingestion/skin contact, and potential to form explosive peroxides. Always use appropriate personal protective equipment, including a full-face respirator, gloves, goggles, and protective clothing, in a well-ventilated area, away from ignition sources and incompatible materials. Refer to the Safety Data Sheet for detailed guidance.
How is 2-Butenylmagnesium chloride solution packed, shipped, and exported?
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This product is classified under UN 2924, UN Hazard Class 8 (Corrosive) with subsidiary risk 3 (Flammable), Packing Group II. It is packed and shipped according to strict international regulations for hazardous materials, suitable for global export.
How can I request a quote or sample for 2-Butenylmagnesium chloride solution?
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To request a quote or sample, please use the contact form on our website or email our sales department directly, providing your details and the product CAS number 22649-70-3.
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