2,4-Difluorobenzylamine
2,4-Difluorobenzylamine (CAS: 72235-52-0) is an organic building block with the molecular formula F2C6H3CH2NH2 and a molecular weight of 143.13 g/mol. This fluorinated amine is primarily utilised in organic synthesis, particularly in the creation of complex molecules. Its structure makes it a valuable intermediate for introducing the 2,4-difluorobenzyl moiety into various chemical structures for research and development purposes.
- Synonyms
- F2C6H3CH2NH2
Organic Synthesis Intermediate
2,4-Difluorobenzylamine serves as a key intermediate in the synthesis of various organic compounds. Its fluorinated aromatic ring and primary amine group offer versatile reactivity for derivatization.
Pharmaceutical Research
This compound has been employed in the synthesis of novel chemical entities, including dipeptides, which may be relevant for pharmaceutical research and drug discovery efforts.
Material Science
Fluorinated organic building blocks like 2,4-difluorobenzylamine can be incorporated into advanced materials, potentially influencing properties such as thermal stability and chemical resistance.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 98% |
| Density | 1.204 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.49(lit.) |
| Application | 2,4-Difluorobenzylamine has been used in the synthesis of βAla–Aib(N-fluoroarylmethyl)], nonpolar nucleobase dipeptide via Ugi four-component condensation reaction1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 68 °C / 154.4 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Difluorobenzylamine used for?
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2,4-Difluorobenzylamine is used as an intermediate in organic synthesis, including the preparation of dipeptides and other fluorinated organic compounds for research and development in areas such as pharmaceuticals and material science.
What is the CAS number and molecular formula for 2,4-Difluorobenzylamine?
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The CAS number for 2,4-Difluorobenzylamine is 72235-52-0, and its molecular formula is F2C6H3CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Difluorobenzylamine with a purity of 98% (assay). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 2,4-Difluorobenzylamine be handled safely?
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2,4-Difluorobenzylamine is a corrosive substance. Handle with appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, a face shield, and a suitable respirator. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 2,4-Difluorobenzylamine exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,4-Difluorobenzylamine.
How can I request a sample or quote for 2,4-Difluorobenzylamine?
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To request a sample or a quotation for 2,4-Difluorobenzylamine, please contact the Tech Serve Solutions sales team via the website or by phone.
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