Zearalenone
Zearalenone (CAS: 17924-92-4, C18H22O5) is a non-steroidal estrogenic mycotoxin produced by various species of Fusarium. This premium grade compound, with a molecular weight of 318.36 g/mol, functions as a potent estrogen modulator. It is widely employed in scientific research for studies related to cell biology, cancer research, and understanding estrogenic effects in biological systems. Zearalenone serves as a valuable tool in investigating endocrine disruption and hormone-dependent processes.
- IUPAC
- F-2 toxin
Estrogen Modulation Research
Zearalenone is utilised in research to investigate the mechanisms of estrogenic compounds and their effects on hormone receptors, particularly the estrogen receptor (Esr1) in mouse models. This aids in understanding endocrine signaling pathways.
Cancer Research Studies
As a compound with significant hormonal activity, Zearalenone is used in cancer research to study its role in hormone-dependent tumor growth and as a potential chemopreventive agent. Investigations focus on its impact on tumor development and progression.
Cell Biology and Signaling
Researchers employ Zearalenone to explore its impact on cellular functions and signaling pathways, particularly those influenced by steroid hormones. This helps in elucidating complex biological responses at the cellular level.
Mycotoxin and Toxin Studies
Zearalenone serves as a model compound in studies of mycotoxins and other naturally occurring toxins. Its well-defined structure and biological activity make it valuable for understanding the toxicological profiles of fungal metabolites.
| Molecular weight | 318.36 |
|---|---|
| Empirical formula | C18H22O5 |
| Concentration | 50 μg/mL in acetonitrile |
| Storage temperature | −20°C |
Hazard statements
- H314Causes severe skin burns and eye damage
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 1759 8 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 63-34-62 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Gene Information | mouse ... Esr1(13982) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Zearalenone used for?
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Zearalenone is primarily used in scientific research for its estrogenic properties, including studies in cancer research, cell biology, cell signaling, neuroscience, and as an estrogen modulator and phytoestrogen analogue. It is also studied for its role as a mycotoxin.
What are the CAS number and formula for Zearalenone?
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The CAS number for Zearalenone is 17924-92-4, and its empirical formula is C18H22O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Zearalenone at a PREMIUM quality level, provided as 50 μg/mL in acetonitrile. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the specifications.
What are the safety and handling precautions for Zearalenone?
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Zearalenone is classified with GHS symbols GHS05 and GHS08, carrying a Danger signal word. It has hazard statements H314 (Causes severe skin burns and eye damage) and H361 (Suspected of damaging fertility or the unborn child). Handle with extreme caution, wearing protective gloves, clothing, eye protection, and face protection. In case of contact, rinse cautiously with water for several minutes and immediately call a POISON CENTER or doctor. Ensure good ventilation during handling.
How is Zearalenone shipped and exported by TSS?
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Zearalenone is shipped and exported under UN 1759, Class 8, Packing Group III (Corrosive solid, acidic, organic, n.o.s.). TSS adheres to all relevant international regulations for the export of chemical compounds.
How can I request a sample or quote for Zearalenone?
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To request a sample or a quotation for Zearalenone, please contact the Tech Serve Solutions sales team through our website or by calling our dedicated customer service line.
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