Z-L-Arg 7-amido-4-methylcoumarin hydrochloride

CAS 70375-22-3C24H27N5O5 · HClBiochemicals & Reagents

Z-L-Arg 7-amido-4-methylcoumarin hydrochloride (CAS: 70375-22-3) is a fluorogenic substrate with the molecular formula C24H27N5O5 · HCl and a molecular weight of 501.96 g/mol. This compound is primarily utilised in biochemical research as an enzyme substrate for detecting protease activity. Its fluorescence properties, with specific excitation and emission wavelengths, make it valuable for quantitative assays.

IUPAC: Carbobenzoxy-L-arginine-7-amino-4-methylcoumarin hydrochloride,Nα-Cbz-L-arginine 7-amido-4-methylcoumarin hydrochloride,Z-L-Arginine-4-methyl-7-coumarinylamide hydrochloride,Z-Arg-MCA
Synonyms: Carbobenzoxy-L-arginine-7-amino-4-methylcoumarin hydrochlorideNα-Cbz-L-arginine 7-amido-4-methylcoumarin hydrochlorideZ-L-Arginine-4-methyl-7-coumarinylamide hydrochlorideZ-Arg-MCA

Email us

Z-L-Arg 7-amido-4-methylcoumarin hydrochloride (C24H27N5O5 · HCl) — chemical structure, CAS 70375-22-3; Life Science, fine chemical supplied by Tech Serve Solutions

ActivityBiochemicals and ReagentsEnzyme SubstratesEnzymesInhibitorsand SubstratesFluorescent ProbesLabelsParticles and StainsFluorogenic

01 /Applications

Enzyme Activity Assays

Serves as a sensitive fluorogenic substrate for the detection and quantification of protease activity, particularly those cleaving arginine residues. The released 7-amino-4-methylcoumarin (AMC) exhibits fluorescence, allowing for continuous monitoring of enzymatic reactions.

Biochemical Research

Utilised in laboratories for studying enzyme kinetics, inhibitor screening, and the characterisation of proteases involved in various biological processes. Its reliable performance aids in understanding enzyme mechanisms.

Fluorescent Labeling

The compound's inherent fluorescence upon cleavage makes it suitable as a tool for developing fluorescent probes in biological imaging and diagnostic applications.

02 /Properties

Molecular weight	501.96
Empirical formula	C24H27N5O5 · HCl
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

70375-22-3

MDL number

MFCD00039019

Beilstein registry

4637954

05 /Additional specifications

Fluorescence	λex 290 nm; λem 390 nm (buffer pH 7.1)λex 290 nm; λem 437 nm ((Reaction product))

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Z-L-Arg 7-amido-4-methylcoumarin hydrochloride used for?

Z-L-Arg 7-amido-4-methylcoumarin hydrochloride is primarily used as a fluorogenic substrate for the detection and quantification of protease activity in biochemical research and enzyme assays.

What is the CAS number and molecular formula?

The CAS number is 70375-22-3 and the molecular formula is C24H27N5O5 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product for research and development purposes. The specific grade and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, EP, BP, or pharmacopoeia grade.

How should Z-L-Arg 7-amido-4-methylcoumarin hydrochloride be handled safely?

Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 (US) respirator filter, as indicated by the safety data. Observe WGK Germany 3 classification and store at -20°C.

Is this product controlled or scheduled?

Based on the provided data, there is no indication that this product is a controlled or scheduled substance.

How can I request a sample or quote?

To request a sample or a quote, please contact our sales department via the website or by phone, providing the product name and CAS number (70375-22-3).

How is this chemical packed, shipped, and exported?

Products are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions. Specific packaging details are confirmed upon order.