Uridine 5′-diphosphate disodium salt hydrate
Uridine 5′-diphosphate disodium salt hydrate (CAS: 27821-45-0) is a nucleotide with the empirical formula C9H12N2Na2O12P2 · xH2O and an anhydrous molecular weight of 448.12. This compound serves as a vital precursor in biochemical research, particularly in studies involving nucleic acid biosynthesis and cell signalling pathways. Upon phosphorylation to Uridine 5′-triphosphate (UTP), it becomes a key substrate for enzymes fundamental to RNA synthesis and cellular regulation. Available from Tech Serve Solutions.
- IUPAC
- 5′-UDP-Na2

Nucleic Acid Biosynthesis Research
Uridine 5′-diphosphate (UDP) is a fundamental component in the study of RNA biosynthesis. Its phosphorylated form, UTP, serves as a direct substrate for RNA polymerases, playing a crucial role in the transcription process.
Cell Signalling Studies
UDP and its phosphorylated derivative UTP are implicated in various cell signalling pathways. They act as substrates for enzymes like GTPases and are involved in the regulation of G-coupled Protein Receptors (GPCR) and intracellular signalling cascades.
Enzyme Substrate Studies
This compound is used to investigate the activity and function of enzymes involved in nucleotide metabolism and signalling. Its role as a precursor to UTP makes it valuable for understanding enzyme kinetics and biological functions.
| Molecular weight | 448.12 (anhydrous basis) |
|---|---|
| Empirical formula | C9H12N2Na2O12P2 · xH2O |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | −20°C |
| Impurities tested | ≤15% water |
| Application | Uridine 5′-diphosphate (UDP) and Uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF). |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Uridine 5′-diphosphate disodium salt hydrate used for?
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Uridine 5′-diphosphate disodium salt hydrate is primarily used in biochemical research for studies on nucleic acid (RNA) biosynthesis and cell signalling. It serves as a precursor to Uridine 5′-triphosphate (UTP), a substrate for enzymes like RNA polymerase and GTPases.
What are the CAS number and formula for this compound?
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The CAS number is 27821-45-0, and the empirical formula is C9H12N2Na2O12P2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Uridine 5′-diphosphate disodium salt hydrate with an assay of ≥96.0% (HPLC). This product is intended for research and laboratory use, and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Uridine 5′-diphosphate disodium salt hydrate?
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This compound is classified as a skin irritant, eye irritant, and respiratory irritant. When handling, use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation. Avoid breathing dust. Avoid contact with eyes, skin, and clothing. In case of contact, rinse cautiously with water for several minutes.
How is this chemical packed, shipped, and exported?
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Uridine 5′-diphosphate disodium salt hydrate is typically stored at −20°C. We adhere to all international regulations for the safe packing, shipping, and export of fine chemicals, ensuring secure and compliant delivery to our global customers.
How can I request a sample or a quote?
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To request a sample or obtain a quotation, please contact our sales team directly through the 'Contact Us' section of our website or by calling our office. Please specify the product name and CAS number (27821-45-0) in your request.
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