Tyloxapol
Tyloxapol (CAS 25301-02-4) is a non-ionic detergent with applications in biological and chemical research. This polymer of 4-(1,1,3,3-tetramethylbutyl)phenol with formaldehyde and oxirane serves as a solubilising agent and emulsifier. Its properties, including a specific cloud point and critical micelle concentration (CMC), make it valuable in various laboratory procedures. Tech Serve Solutions supplies Tyloxapol as a premium grade product for research and development purposes.
- IUPAC
- 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane

Solubilisation of Biological Molecules
Tyloxapol is frequently employed to solubilise hydrophobic or poorly soluble biological molecules, such as membrane proteins and lipids, facilitating their extraction and study. Its detergent properties aid in breaking down complex biological structures.
Biochemical Assays and Research
In biochemical research, Tyloxapol can be used in various assay formats to improve the solubility of substrates or reagents, thereby enhancing assay performance. It is a component in certain buffer formulations for sensitive experiments.
Emulsification and Dispersion
As a non-ionic surfactant, Tyloxapol can act as an emulsifier or dispersant in laboratory preparations. It helps to stabilise mixtures of immiscible substances, which is useful in certain analytical and experimental setups.
| Impurities tested | <0.0005% Phosphorus (P) |
|---|---|
| Application | Do you have application information on this product that you would like to share? |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | Al: Ca: Cu: Fe: K: Mg: NH4+: Na: Pb: Zn: <0.0005% |
| Anion traces | chloride (Cl-): sulfate (SO42-): <0.6% |
| Ignition residue | <1.0% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|---|
| Transition Temp | cloud point 94.3 °C |
| Cmc | 0.018 mM |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tyloxapol used for?
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Tyloxapol is primarily used as a non-ionic detergent for solubilising biological molecules, in biochemical assays, and as an emulsifier or dispersant in laboratory applications.
What is the CAS number and chemical formula for Tyloxapol?
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The CAS number for Tyloxapol is 25301-02-4. The chemical formula is provided as 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tyloxapol as a PREMIUM grade. Purity details, such as specific impurity levels and transition temperatures, are available in the product specifications. We do not represent this product as USP, BP, or EP grade.
How should Tyloxapol be handled safely?
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Tyloxapol is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator if necessary.
Is Tyloxapol a controlled substance?
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Based on the provided data, Tyloxapol is not indicated as a controlled substance.
How is Tyloxapol packed and shipped?
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Tyloxapol is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Tyloxapol?
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To request a sample or a quote for Tyloxapol, please contact our sales team through the website or via the provided contact details.
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