Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride
Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride (CAS 99662-46-1) is a Wittig reagent with the molecular formula C24H21ClNP · HCl and a molecular weight of 426.32. This compound is supplied by Tech Serve Solutions with an assay of 98%. It is primarily utilized as a reactant in C-C bond formation, chemical synthesis, olefination reactions, and the preparation of specialized organic molecules such as catechol derivatives and naphthalene-based protease inhibitors.

Isomerization Reactions
Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride serves as a reactant in isomerization reactions, facilitating the rearrangement of molecular structures to achieve desired isomers.
Fluorescent Chemosensors
This phosphonium salt is employed in the preparation of catechol derivatives, which are subsequently developed into fluorescent chemosensors for wide-range pH detection.
Protease Inhibitor Synthesis
It is used in the synthesis of naphthalene derivatives that exhibit inhibitory activity against human cytomegalovirus (HCMV) protease, contributing to antiviral research.
Wittig Reagent Applications
As a Wittig reagent, it is integral to olefination reactions, enabling the formation of carbon-carbon double bonds, a fundamental transformation in organic synthesis.
| Molecular weight | 426.32 |
|---|---|
| Empirical formula | C24H21ClNP · HCl |
| Assay | 98% |
| Application | Reactant for:• Isomerization reactions1• Preparation of catechol derivatives as fluorescent chemosensors for wide-range pH detection2• Preparation of naphthalene derivatives as human cytomegalovirus (HCMV) protease inhibitors3 |
| Melting point | 249-254 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride used for?
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Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride is used as a reactant in isomerization reactions, for the preparation of catechol derivatives as fluorescent chemosensors for pH detection, and for the preparation of naphthalene derivatives as human cytomegalovirus (HCMV) protease inhibitors. It is also broadly applied in C-C bond formation, chemical synthesis, olefination, and as a synthetic reagent, particularly in Wittig reactions.
What is the CAS number and molecular formula?
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The CAS number for Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride is 99662-46-1, and its empirical formula is C24H21ClNP · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride with an assay of 98%. This is a technical or research grade product, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is classified with GHS07 and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is this product packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations and can be exported worldwide.
How can I request a sample or quote?
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To request a sample or a quote for Triphenyl(2-pyridylmethyl)phosphonium chloride hydrochloride, please contact our sales team through the website or by phone.
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