Trimethylsulfoxonium chloride
Trimethylsulfoxonium chloride (CAS: 5034-06-0), with the molecular formula (CH3)3S(Cl)O and a molecular weight of 128.62 g/mol, is a chemical reagent. It is primarily recognised as a precursor for the generation of dimethyloxosulfonium methylide. This ylide is a valuable tool in organic synthesis, particularly for its role in C-C bond formation reactions. The compound is supplied by TSS with an assay of 98%.
- IUPAC
- NSC 221182

Precursor to Dimethyloxosulfonium Methylide
Trimethylsulfoxonium chloride is a key reagent for synthesising dimethyloxosulfonium methylide. This ylide is employed in cyclopropanation reactions and epoxide formation, enabling the construction of strained ring systems.
C-C Bond Formation
The dimethyloxosulfonium methylide generated from this precursor can be used in various carbon-carbon bond-forming reactions. It serves as a nucleophilic methylene transfer agent, contributing to the synthesis of complex organic molecules.
Organic Synthesis
As a versatile building block and reagent precursor, Trimethylsulfoxonium chloride finds utility in diverse synthetic pathways within academic and industrial research settings. Its applications span the creation of novel chemical entities.
| Molecular weight | 128.62 |
|---|---|
| Linear formula | (CH3)3S(Cl)O |
| Assay | 98% |
| Application | Precursor to dimethyloxosulfonium methylide. |
| Melting point | 226-229 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylsulfoxonium chloride used for?
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Trimethylsulfoxonium chloride is primarily used as a precursor to dimethyloxosulfonium methylide, a reagent valuable for C-C bond formation and other synthetic transformations in organic chemistry.
What is the CAS number and formula for Trimethylsulfoxonium chloride?
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The CAS number for Trimethylsulfoxonium chloride is 5034-06-0, and its linear formula is (CH3)3S(Cl)O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethylsulfoxonium chloride with a purity of 98%. This product is suitable for research and general chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should Trimethylsulfoxonium chloride be handled safely?
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Handle Trimethylsulfoxonium chloride with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid inhalation of dust. Refer to the Safety Data Sheet for comprehensive handling information. It is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is Trimethylsulfoxonium chloride a controlled substance?
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Based on the provided data, Trimethylsulfoxonium chloride is not listed as a controlled substance.
How is Trimethylsulfoxonium chloride packed and shipped?
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Trimethylsulfoxonium chloride is carefully packed to ensure safe transit and is exported globally by TSS according to relevant shipping regulations.
How can I request a sample or quote for Trimethylsulfoxonium chloride?
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To request a sample or obtain a quote for Trimethylsulfoxonium chloride, please contact our sales team through the TSS website or by direct inquiry, providing your specific requirements.
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