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Trimethyl(propargyl)silane

CAS 13361-64-3HC≡CCH2Si(CH3)3Chemical Synthesis

Trimethyl(propargyl)silane (CAS: 13361-64-3; Formula: HC≡CCH₂Si(CH₃)₃) is an organosilicon compound with a molar mass of 112.24 g/mol. This versatile chemical serves as a valuable building block in organic synthesis. Its terminal alkyne functionality, protected by a trimethylsilyl group, allows for controlled reactions and further functionalization in the creation of complex organic molecules.

IUPAC
2-Propynyl-trimethylsilane,3-(Trimethylsilyl)propyne
Synonyms
2-Propynyl-trimethylsilane3-(Trimethylsilyl)propyne
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Trimethyl(propargyl)silane (HC≡CCH2Si(CH3)3) — chemical structure, CAS 13361-64-3; Chemistry, fine chemical supplied by Tech Serve Solutions
AlkynesBuilding BlocksChemical SynthesisOrganic Building BlocksTerminal
01 /Applications

Organic Synthesis Intermediate

Trimethyl(propargyl)silane is widely employed as a synthetic intermediate in the construction of complex organic frameworks. Its structure allows for selective modifications, making it useful in multi-step syntheses.

Building Block for Heterocycles

This compound can be utilized in the synthesis of various heterocyclic compounds. The propargyl group can participate in cyclization reactions, leading to diverse ring systems.

Precursor for Functionalized Alkynes

The trimethylsilyl group can be selectively removed under specific conditions, revealing a terminal alkyne ready for further reactions such as Sonogashira coupling or click chemistry.

02 /Properties
Molecular weight112.24
Linear formulaHC≡CCH2Si(CH3)3
Boiling point91-93 °C(lit.)
Density0.753 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.413(lit.)
Storage temperature−20°C
Contains / stabiliser500 ppm BHT as stabilizer≤20% trimethylallenylsilane (in equilibrium)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point-5 °C / 23 °F
Transport (UN / ADR)UN 1993BF 3 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-36/37/38
Safety statements (S)16-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
13361-64-3
MDL number
MFCD00042922
PubChem substance
24863432
Beilstein registry
2036316
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trimethyl(propargyl)silane used for?

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Trimethyl(propargyl)silane is primarily used as a building block and intermediate in organic synthesis for constructing complex molecules and functionalized alkynes.

What are the CAS number and chemical formula for Trimethyl(propargyl)silane?

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The CAS number is 13361-64-3, and the chemical formula is HC≡CCH₂Si(CH₃)₃.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Trimethyl(propargyl)silane at a technical/research grade. We do not represent this product as USP, BP, or EP grade.

How should Trimethyl(propargyl)silane be handled safely?

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Trimethyl(propargyl)silane is a flammable liquid and vapour (H225). It is a skin irritant (H315), eye irritant (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area away from ignition sources.

Is Trimethyl(propargyl)silane flammable?

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Yes, Trimethyl(propargyl)silane is flammable with a flash point of -5 °C (23 °F) and is classified as H225: Highly flammable liquid and vapour.

How is Trimethyl(propargyl)silane packed and shipped?

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Trimethyl(propargyl)silane is typically packed in suitable containers for hazardous materials and can be exported globally by Tech Serve Solutions in compliance with transport regulations.

How can I request a quote or sample for Trimethyl(propargyl)silane?

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To request a quote or sample, please contact our sales department through the website or by phone, providing your specific requirements.

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