Tributyl orthoformate
Tributyl orthoformate (CAS 588-43-2), with the linear formula CH[O(CH2)3CH3]3 and a molecular weight of 232.36 g/mol, is a chemical compound belonging to the ortho ester class. This substance serves as a versatile building block in organic synthesis, often employed in the formation of acetals and ketals. Its utility extends to various chemical processes requiring a stable source of the formyl group.
![Tributyl orthoformate (CH[O(CH2)3CH3]3) — chemical structure, CAS 588-43-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F588-43-2.png&w=3840&q=75)
Organic Synthesis Reagent
Tributyl orthoformate functions as a key reagent in organic synthesis, particularly for the introduction of the formyl group or in acetalization reactions. It is valuable for protecting carbonyl compounds or creating specific functional groups in complex molecules.
Building Block for Heterocycles
This ortho ester is utilised as a building block in the synthesis of various heterocyclic compounds. Its reactivity allows for the construction of diverse ring systems important in medicinal chemistry and materials science.
Intermediate in Pharmaceutical Manufacturing
The compound can serve as an intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific chemical properties make it suitable for certain transformations within pharmaceutical production pathways.
| Molecular weight | 232.36 |
|---|---|
| Linear formula | CH[O(CH2)3CH3]3 |
| Assay | ≥99.0% (GC) |
| Boiling point | 120-122 °C/15 mmHg(lit.) |
| Density | 0.872 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.418 |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tributyl orthoformate used for?
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Tributyl orthoformate is primarily used as a reagent in organic synthesis for formylation and acetalization reactions, and as a building block for heterocyclic compounds and pharmaceutical intermediates.
What are the CAS number and formula for Tributyl orthoformate?
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The CAS number for Tributyl orthoformate is 588-43-2, and its linear formula is CH[O(CH2)3CH3]3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tributyl orthoformate with a purity of ≥99.0% as determined by GC. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, or EP grade.
How should Tributyl orthoformate be handled safely?
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Handling Tributyl orthoformate requires appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection such as a multi-purpose combination respirator cartridge or a type ABEK respirator filter is recommended. The compound is combustible with a flash point of 89 °C (192.2 °F).
Is Tributyl orthoformate a controlled substance?
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Based on the provided data, Tributyl orthoformate (CAS 588-43-2) is not indicated as a controlled substance. However, users should always verify local regulations.
How is Tributyl orthoformate packed and shipped?
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Tributyl orthoformate is classified under NA 1993 / PGIII for transport. TSS ensures appropriate packaging for safe handling, export, and global distribution of this chemical.
How can I request a sample or quote for Tributyl orthoformate?
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To request a sample or a quotation for Tributyl orthoformate, please contact the Tech Serve Solutions sales team through our website or by phone.
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