Tribenzylphosphine
Tribenzylphosphine (CAS 7650-89-7) is a phosphine compound with the linear formula (C6H5CH2)3P and a molecular weight of 304.37 g/mol. It serves as a valuable cocatalyst in various organic synthesis reactions. Its applications span nickel-catalyzed cycloadditions for coumarin synthesis, copolymerization, and rhodium-catalyzed hydroformylation, highlighting its versatility in modern chemical transformations.
Cocatalyst in Cycloaddition Reactions
Tribenzylphosphine acts as a cocatalyst in the preparation of coumarin derivatives through nickel-catalyzed cycloaddition reactions, enabling efficient synthesis pathways.
Copolymerization Reactions
This phosphine compound finds utility as a cocatalyst in various copolymerization reactions, contributing to the synthesis of complex polymeric materials.
Hydroformylation Reactions
It serves as a cocatalyst in rhodium-catalyzed hydroformylation reactions, a crucial process for the production of aldehydes from alkenes.
Oxidative Hydroxylation
Tribenzylphosphine is employed as a cocatalyst in platinum-catalyzed oxidative hydroxylation reactions, facilitating the introduction of hydroxyl groups.
Three-Component Coupling
It plays a role as a cocatalyst in the preparation of substituted allylamines via three-component coupling of alkynes, imines, and organoboranes.
Metathesis Reactions
This compound is utilised in ruthenium-catalyzed metathesis reactions, specifically noted for its role in degenerate ligand exchange processes.
| Molecular weight | 304.37 |
|---|---|
| Linear formula | (C6H5CH2)3P |
| Assay | 98% |
| Application | Cocatalyst in:• Preparation of coumarin derivatives via nickel-catalyzed cycloaddition1• Copolymerization reactions2• Rh-catalyzed hydroformylation reactions3• Platinum-catalyzed oxidative hydroxylation reactions4• Preparation of substituted allylamines by three-component coupling of alkynes, imines and organoboranes5• Ruthenium catalyzed metathesis reactions (Degenerate ligand exchange)6 |
| Melting point | 96-101 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tribenzylphosphine used for?
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Tribenzylphosphine is primarily used as a cocatalyst in various organic synthesis reactions, including the preparation of coumarin derivatives, copolymerization, hydroformylation, oxidative hydroxylation, three-component coupling reactions, and ruthenium-catalyzed metathesis reactions.
What is the CAS number and formula for Tribenzylphosphine?
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The CAS number for Tribenzylphosphine is 7650-89-7, and its linear formula is (C6H5CH2)3P.
What grade and purity does Tech Serve Solutions supply for Tribenzylphosphine?
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Tech Serve Solutions supplies Tribenzylphosphine with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Tribenzylphosphine be handled safely?
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Tribenzylphosphine is classified with GHS07 and the signal word 'Warning', with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is Tribenzylphosphine exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tribenzylphosphine.
How can I request a quote or sample for Tribenzylphosphine?
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To request a quote or sample for Tribenzylphosphine, please contact our sales team through the website or provide your details via the product inquiry form.
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