trans-4-Nitrocinnamoyl chloride
trans-4-Nitrocinnamoyl chloride (CAS 61921-33-3) is an organic acid halide with the linear formula O₂NC₆H₄CH=CHCOCl and a molecular weight of 211.60. This compound serves as a valuable intermediate and building block in organic synthesis. Its reactive acyl chloride group facilitates esterification and amidation reactions, making it useful in the preparation of various complex organic molecules. It is primarily employed in chemical research and development settings.

Organic Synthesis Intermediate
Utilised as a reactive intermediate in the synthesis of diverse organic compounds. The acyl chloride functionality readily participates in reactions with nucleophiles like alcohols and amines.
Building Block for Complex Molecules
Acts as a key building block for constructing more elaborate molecular structures. Its utility is particularly noted in research laboratories for novel compound development.
Research and Development
Employed in academic and industrial research settings for exploring new synthetic pathways and creating novel chemical entities.
| Molecular weight | 211.60 |
|---|---|
| Linear formula | O2NC6H4CH=CHCOCl |
| Assay | 97% |
| Melting point | 150-153 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-4-Nitrocinnamoyl chloride used for?
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trans-4-Nitrocinnamoyl chloride is primarily used as an intermediate and building block in organic synthesis and in research and development for the creation of complex organic molecules.
What is the CAS number and formula for trans-4-Nitrocinnamoyl chloride?
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The CAS number is 61921-33-3 and the linear formula is O₂NC₆H₄CH=CHCOCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-4-Nitrocinnamoyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should trans-4-Nitrocinnamoyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 US / P3 EN143). Refer to the safety data sheet for comprehensive handling instructions.
How is trans-4-Nitrocinnamoyl chloride shipped and exported?
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The compound is regulated for transport under UN 3261, Class 8, Packing Group II. Tech Serve Solutions handles the export of this chemical in compliance with all relevant international shipping regulations.
How can I request a sample or quote for trans-4-Nitrocinnamoyl chloride?
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To request a sample or a quote, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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