trans-2-Chloromethylvinylboronic acid
Tech Serve Solutions (TSS) presents trans-2-Chloromethylvinylboronic acid (CAS: 215951-86-3), a crucial organometallic reagent with the linear formula ClCH<sub>2</sub>CH=CHB(OH)<sub>2</sub> and a molecular weight of 120.34. This boronic acid derivative serves as a valuable building block in organic synthesis, primarily recognised for its utility in Suzuki-Miyaura cross-coupling reactions. Its specific structure enables the introduction of a chloromethylvinyl moiety into various molecular frameworks, facilitating the construction of complex organic molecules.
Suzuki-Miyaura Cross-Coupling Reactions
This compound is an effective reactant in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds. It enables the coupling of the vinylboronic acid moiety with organic halides or pseudohalides.
Organic Synthesis Building Block
As a functionalised boronic acid, trans-2-Chloromethylvinylboronic acid serves as a versatile building block in the synthesis of complex organic molecules. Its structure allows for further functionalisation or incorporation into larger molecular architectures.
Intermediate for Pharmaceutical Research
The unique chloromethylvinyl group makes this compound a potential intermediate in the research and development of novel pharmaceutical compounds. Its application may lie in the synthesis of active pharmaceutical ingredients (APIs) or their precursors.
| Molecular weight | 120.34 |
|---|---|
| Linear formula | ClCH2CH=CHB(OH)2 |
| Application | • Reactant for Suzuki-Miyaura cross-coupling reaction1 |
| Melting point | 110-113 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-2-Chloromethylvinylboronic acid used for?
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trans-2-Chloromethylvinylboronic acid is primarily used as a reactant in Suzuki-Miyaura cross-coupling reactions and as a building block in organic synthesis for constructing complex molecules, including potential pharmaceutical intermediates.
What is the CAS number and formula for trans-2-Chloromethylvinylboronic acid?
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The CAS number is 215951-86-3 and the linear formula is ClCH<sub>2</sub>CH=CHB(OH)<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-2-Chloromethylvinylboronic acid primarily as a research or technical grade chemical. The specific assay and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
What are the safety and handling precautions for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating a high hazard level. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is trans-2-Chloromethylvinylboronic acid packed, shipped, and exported?
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This chemical is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, adhering to all relevant shipping regulations for hazardous materials.
How can I request a quote or sample for trans-2-Chloromethylvinylboronic acid?
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To request a quote or a sample of trans-2-Chloromethylvinylboronic acid, please contact the TSS sales team through our website or by phone, providing your specific requirements.
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