trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester
trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester (CAS 1073354-58-1) is an organoboron compound with the molecular formula C14H17BF2O2. This alkenyl boronate ester serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its unique difluorophenylvinyl moiety makes it an important intermediate for the preparation of complex molecules within the pharmaceutical and materials science sectors.
- IUPAC
- (E)-2-(3,5-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,2-[(1E)-2-(3,5-Difluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,trans-2-(3,5-Difluorophenyl)vinyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Synonyms
- C14H17BF2O2(E)-2-(3,5-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane2-[(1E)-2-(3,5-Difluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolanetrans-2-(3,5-Difluorophenyl)vinyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Organic Synthesis Intermediate
This compound is a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. It is instrumental in constructing complex organic molecules.
Pharmaceutical Research
Utilised in the synthesis of novel pharmaceutical candidates and active pharmaceutical ingredients (APIs). The difluorophenyl group can impart desirable pharmacokinetic properties.
Materials Science
Can be incorporated into the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or specialized polymers, where its electronic and structural properties are advantageous.
| Molecular weight | 266.09 |
|---|---|
| Empirical formula | C14H17BF2O2 |
| Assay | ≥96% |
| Boiling point | 127-130 °C/2.4 mmHg |
| Density | 1.084 g/mL at 25 °C |
| Refractive index | n20/D 1.5002 |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester used for?
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trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the creation of complex organic molecules, including intermediates for pharmaceutical research and materials science applications.
What is the CAS number and molecular formula?
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The CAS number for trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester is 1073354-58-1. Its molecular formula is C14H17BF2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester with an assay of ≥96%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should this chemical be handled and stored?
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This compound has a flash point greater than 110 °C (230 °F), indicating it is combustible. Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling, storage, and disposal information. The WGK Germany is 3.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester. We handle international shipping and export procedures.
How can I request a sample or quote?
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To request a sample or a quote for trans-2-(3,5-Difluorophenyl)vinyl boronic acid pinacol ester, please contact our sales department through the website or by phone, providing the product name and CAS number (1073354-58-1).
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