trans-1-Acetyl-4-hydroxy-L-proline
Trans-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7), a derivative of the amino acid proline with the chemical formula C7H11NO4 and a molecular weight of 173.17 g/mol, is a key chiral building block. It finds utility in chemical synthesis and peptide chemistry, particularly in the creation of modified peptides and complex organic molecules. This compound serves as a valuable reagent for researchers in chemical biology and medicinal chemistry.

Chemical Synthesis
Serves as a chiral building block for the synthesis of complex organic molecules. Its defined stereochemistry is crucial for asymmetric synthesis.
Peptide Chemistry
Used in the construction of unnatural peptides and peptidomimetics. It allows for the introduction of modified proline residues into peptide chains.
Chemical Biology
A valuable reagent for probing biological systems and developing novel bioactive compounds. Its structure can be incorporated into molecules designed to interact with specific biological targets.
Proline Derivatives Research
Facilitates research into the structure-activity relationships of proline derivatives. Enables the study of how modifications to the proline ring affect molecular properties.
| Molecular weight | 173.17 |
|---|---|
| Empirical formula | C7H11NO4 |
| Assay | ≥99.0% (T) |
| Optical activity | [α]20/D −119±2°, c = 4% in H2O |
| Melting point | 130-133 °C |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is trans-1-Acetyl-4-hydroxy-L-proline used for?
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Trans-1-Acetyl-4-hydroxy-L-proline is used in chemical synthesis, peptide chemistry, chemical biology, and as a proline derivative for research purposes, serving as a chiral building block and a reagent for creating modified peptides and complex organic molecules.
What are the CAS number and formula for trans-1-Acetyl-4-hydroxy-L-proline?
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The CAS number is 33996-33-7 and the empirical formula is C7H11NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies trans-1-Acetyl-4-hydroxy-L-proline with an assay of ≥99.0% (T). We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
How should trans-1-Acetyl-4-hydroxy-L-proline be handled?
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Due to its potential to cause serious eye damage, appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US), should be worn. Handle in a well-ventilated area and avoid dust formation.
How is trans-1-Acetyl-4-hydroxy-L-proline packed, shipped, and exported?
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Trans-1-Acetyl-4-hydroxy-L-proline is available for global export. Packaging is designed to maintain product integrity during transit, adhering to international shipping regulations.
How can I request a sample or quote for trans-1-Acetyl-4-hydroxy-L-proline?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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