Tirofiban hydrochloride monohydrate
Tirofiban hydrochloride monohydrate (CAS: 150915-40-5), with the formula C22H36N2O5S·HCl·H2O and a molecular weight of 495.07, is a potent and selective tyrosine kinase inhibitor. Primarily recognised for its role as an antiplatelet agent, it reversibly blocks the platelet glycoprotein IIb/IIIa receptor, crucial for platelet aggregation. This compound is invaluable in research settings for studying platelet function, thrombosis, and cardiovascular disease mechanisms.
- IUPAC
- L 700462,MK 383,N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
- Synonyms
- L 700462MK 383N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
Antiplatelet Research
Tirofiban hydrochloride monohydrate serves as a vital tool in pharmacological research to investigate the mechanisms of platelet aggregation and its role in thrombotic disorders. Its selective inhibition of the GPIIb/IIIa receptor makes it ideal for in vitro and in vivo studies.
Cardiovascular Disease Modelling
In preclinical research, this compound is used to model conditions related to acute coronary syndromes and to evaluate the efficacy of novel antithrombotic strategies. It aids in understanding the complex pathways involved in cardiovascular diseases.
Biochemical Assays
The molecule is employed in biochemical assays to characterise receptor-ligand interactions and to screen for other compounds that modulate platelet function. Its well-defined inhibitory profile allows for precise experimental design.
| Molecular weight | 495.07 |
|---|---|
| Empirical formula | C22H36N2O5S·HCl·H2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: >12 mg/mL at warmed to 60 °C |
| Optical activity | [α]/D -10 to -18° (c=1, MeOH) |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tirofiban hydrochloride monohydrate used for?
+
Tirofiban hydrochloride monohydrate is primarily used in research as a potent and selective inhibitor of the platelet glycoprotein IIb/IIIa receptor, making it valuable for studying platelet aggregation, thrombosis, and cardiovascular disease mechanisms.
What are the CAS number and formula for Tirofiban hydrochloride monohydrate?
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The CAS number for Tirofiban hydrochloride monohydrate is 150915-40-5, and its molecular formula is C22H36N2O5S·HCl·H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tirofiban hydrochloride monohydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations for handling Tirofiban hydrochloride monohydrate?
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Tirofiban hydrochloride monohydrate is a Warning substance (GHS07) that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, ensuring adequate ventilation.
How is Tirofiban hydrochloride monohydrate shipped and stored?
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This compound is shipped in wet ice. For optimal stability, it should be stored desiccated at -20°C.
How can I request a sample or quote for Tirofiban hydrochloride monohydrate?
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To request a sample or a quote, please contact our sales team via the website or direct email, providing your specific requirements.
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