Thiocholesterol
Thiocholesterol (CAS: 1249-81-6; Formula: C27H46S) is a sterol lipid derived from cholesterol. This compound possesses a molecular weight of 402.72 g/mol and exhibits optical activity with a specific rotation of [α]20/D −23°. Thiocholesterol is primarily utilised in biological research, particularly for its applications in cross-linking studies and investigations into cellular membranes. It serves as a valuable reagent in biochemical and chemical synthesis research.
- IUPAC
- 5-Cholestene-3β-thiol,Cholesteryl mercaptan
- Synonyms
- 5-Cholestene-3beta-thiolCholesteryl mercaptan
Biological Cross-linking Studies
Thiocholesterol is employed in biological research for its utility in cross-linking applications. This helps researchers to investigate molecular interactions and structural properties within biological systems.
Membrane Studies
The compound serves as a reagent in studies focused on cellular membranes. Its sterol structure allows for investigations into lipid-protein interactions and membrane dynamics.
Biochemical Reagent
As a biochemical reagent, Thiocholesterol is valuable for various laboratory procedures and assays. Its unique structure facilitates specific biochemical reactions and analyses.
Chemical Synthesis
Thiocholesterol can be utilised as a building block or intermediate in complex organic synthesis pathways. Its sterol scaffold is useful for creating more intricate molecular architectures.
| Molecular weight | 402.72 |
|---|---|
| Empirical formula | C27H46S |
| Optical activity | [α]20/D −23°, c = 1 in chloroform |
| Storage temperature | 2-8°C |
| Application | Used in biological cross-linking1 and membrane2 studies. |
| Melting point | 97-99 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thiocholesterol used for?
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Thiocholesterol is used in biological cross-linking and membrane studies. It also functions as a biochemical reagent and in chemical synthesis.
What are the CAS number and formula for Thiocholesterol?
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The CAS number for Thiocholesterol is 1249-81-6, and its empirical formula is C27H46S.
What grade and purity does Tech Serve Solutions supply for Thiocholesterol?
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Tech Serve Solutions supplies Thiocholesterol with an assay of 97-99% (MP 97-99 °C). This is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should Thiocholesterol be handled and stored?
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Handle Thiocholesterol with appropriate personal protective equipment, including eyeshields and gloves. A P1 (EN143) or N95 respirator filter is recommended. Store in a cool environment at 2-8°C.
Is Thiocholesterol a controlled substance?
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The provided data does not indicate that Thiocholesterol is a controlled substance.
How is Thiocholesterol packed and exported?
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Thiocholesterol is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Thiocholesterol?
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To request a sample or a detailed quote for Thiocholesterol, please contact our sales department through the website or by phone.
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