Thio-L-citrulline
Thio-L-citrulline (CAS: 156719-37-8), with the molecular formula C6H13N3O2S and a molecular weight of 191.25 g/mol, is an unnatural amino acid derivative. It finds utility as a research chemical in various biological and chemical investigations. Its structural similarity to endogenous compounds makes it a valuable tool in studies related to cellular processes and biochemical pathways, particularly within the fields of chemical biology and peptide chemistry.
- IUPAC
- (S)-2-Amino-5-(thioureido)pentanoic acid,N5-Aminothioxomethyl-L-ornithine

Chemical Biology Research
Thio-L-citrulline serves as a valuable tool in chemical biology for investigating enzyme mechanisms and cellular signaling pathways. Its unnatural structure allows for specific probes in biological systems.
Peptide Synthesis
This compound can be incorporated into synthetic peptides to study structure-activity relationships or to introduce novel functionalities. It is a useful building block in peptide chemistry.
Biochemical Studies
As a derivative of citrulline, Thio-L-citrulline is employed in biochemical research to explore metabolic pathways and enzyme kinetics, especially those involving amino acids and their analogues.
Cell Biology Investigations
Researchers utilize Thio-L-citrulline to investigate cellular processes, potentially impacting cell growth, signaling, or response mechanisms. It aids in understanding the roles of amino acid metabolism within cells.
| Molecular weight | 191.25 |
|---|---|
| Empirical formula | C6H13N3O2S |
| Assay | ≥98.0% |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NOS2(4843)mouse ... Nos2(18126)rat ... Nos1(24598), Nos2(24599) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Thio-L-citrulline used for?
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Thio-L-citrulline is used as a research chemical in chemical biology, peptide synthesis, biochemical studies, and cell biology investigations. It is a tool for exploring enzyme mechanisms, metabolic pathways, and cellular processes.
What are the CAS number and molecular formula for Thio-L-citrulline?
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The CAS number for Thio-L-citrulline is 156719-37-8, and its molecular formula is C6H13N3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Thio-L-citrulline with an assay of ≥98.0%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated in the specifications.
What are the safety and handling recommendations for Thio-L-citrulline?
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Based on available data, individuals handling Thio-L-citrulline should use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. The product carries a WGK Germany classification of 3.
How is Thio-L-citrulline stored and shipped?
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Thio-L-citrulline should be stored at -20°C. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping regulations.
How can I request a quote or sample for Thio-L-citrulline?
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To request a quote or sample for Thio-L-citrulline, please contact our sales team through the website or by phone. Our experts will assist you with your inquiry.
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