Tetramethylammonium iodide
Tetramethylammonium iodide (CAS: 75-58-1) is a quaternary ammonium salt with the linear formula (CH3)4N(I). It presents as a solid, typically supplied at 99% purity. This compound is primarily utilised in chemical synthesis as a reagent for the facile iodination of various organic compounds, including aromatic systems, carboxylic acids, and alcohols. Its applications span across organic synthesis and as a phase transfer catalyst, making it a valuable component in laboratory and industrial chemical processes.

Aromatic Iodination Reagent
Tetramethylammonium iodide serves as an effective reagent for the direct iodination of aromatic compounds. It is particularly useful for introducing iodine into anilines, carboxylic acids, and alcohols with good regioselectivity.
Organic Synthesis Intermediate
As a versatile building block in organic synthesis, this compound facilitates various transformations. Its utility extends to the preparation of complex organic molecules in academic and industrial research settings.
Phase Transfer Catalyst
The quaternary ammonium structure allows Tetramethylammonium iodide to function as a phase transfer catalyst, aiding reactions between reactants in different phases, thus enhancing reaction rates and yields.
| Molecular weight | 201.05 |
|---|---|
| Linear formula | (CH3)4N(I) |
| Assay | 99% |
| Application | Facile iodination of aromatic compounds including anilines, acids and alcohols.1 |
| Melting point | >300 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium iodide used for?
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Tetramethylammonium iodide is used in organic synthesis for the facile iodination of aromatic compounds, anilines, acids, and alcohols. It can also function as a phase transfer catalyst.
What is the CAS number and formula for Tetramethylammonium iodide?
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The CAS number for Tetramethylammonium iodide is 75-58-1, and its linear formula is (CH3)4N(I).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium iodide with a purity of 99%. This product is not classified as USP, BP, or EP grade.
How should Tetramethylammonium iodide be handled safely?
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Tetramethylammonium iodide is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US). Ensure adequate ventilation.
Is Tetramethylammonium iodide a controlled substance?
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Based on the provided data, Tetramethylammonium iodide is not listed as a controlled substance.
How is Tetramethylammonium iodide packed and shipped?
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Tech Serve Solutions can export and ship chemicals globally. Specific packing details are available upon request and are compliant with international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of Tetramethylammonium iodide, please contact our sales team through the TSS website or by phone.
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