Tetramethylammonium hydroxide solution
Tetramethylammonium hydroxide solution (CAS 75-59-2), with the linear formula (CH₃)₄N(OH) and a molecular weight of 91.15 g/mol, is a strong organic base. Supplied as an ACS reagent grade in aqueous solution, it serves as a vital reagent in chemical synthesis and research. Its alkaline properties make it suitable for a range of applications requiring a non-metallic hydroxide base, particularly in electronics manufacturing and organic chemistry.

Electronics Manufacturing
Used as an etchant in semiconductor fabrication, particularly for anisotropic etching of silicon. Its selectivity and non-metallic nature are advantageous for creating precise microelectronic structures.
Phase Transfer Catalysis
Acts as a phase transfer catalyst in various organic reactions. It facilitates the transfer of anionic reactants from an aqueous phase to an organic phase, enhancing reaction rates and yields.
Organic Synthesis
Employed as a strong base in deprotonation reactions and as a precursor for other tetramethylammonium salts. It is valuable in synthesising complex organic molecules.
Laboratory Reagent
Serves as a fundamental reagent in academic and industrial research laboratories for a variety of analytical and synthetic procedures. Its reliable strength and purity are essential for reproducible results.
| Molecular weight | 91.15 |
|---|---|
| Linear formula | (CH3)4N(OH) |
| Grade | ACS reagent |
| Colour | APHA: ≤10 |
| Boiling point | 100 °C |
| Density | 1.005 g/mL at 25 °C |
| Refractive index | n20/D 1.3497 |
| Concentration | 1.0 M±0.02 M in H2O |
| Vapour pressure | 17.5 mmHg (20 °C) |
| Impurities tested | ≤10% water≤2% chloride |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1835 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Cation traces | K: ≤2 ppmNa: ≤2 ppm |
| Anion traces | chloride (Cl-): ≤0.03% |
| Ignition residue | ≤5 ppm |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium hydroxide solution used for?
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Tetramethylammonium hydroxide solution (CAS 75-59-2) is used in electronics manufacturing for etching, as a phase transfer catalyst in organic synthesis, and as a general laboratory reagent for various chemical procedures.
What is the CAS number and formula for Tetramethylammonium hydroxide solution?
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The CAS number is 75-59-2, and the linear formula is (CH₃)₄N(OH).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium hydroxide solution in ACS reagent grade, typically as a 1.0 M ± 0.02 M solution in water. We do not represent this product as USP, BP, or EP grade.
How should Tetramethylammonium hydroxide solution be handled?
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Tetramethylammonium hydroxide solution is a corrosive danger. Handle with appropriate personal protective equipment including gloves, goggles, and face shield. Ensure adequate ventilation and consult the Safety Data Sheet (SDS) for full handling instructions.
Is Tetramethylammonium hydroxide solution a controlled substance?
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Based on the provided data, Tetramethylammonium hydroxide solution (CAS 75-59-2) is not listed as a controlled substance. However, users should always verify local regulations.
How is Tetramethylammonium hydroxide solution packed, shipped, and exported?
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Tetramethylammonium hydroxide solution is shipped and exported by Tech Serve Solutions in compliance with all relevant transportation regulations for hazardous materials (UN 1835, Class 8, PG II).
How can I request a sample or quote for Tetramethylammonium hydroxide solution?
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To request a sample or a quote for Tetramethylammonium hydroxide solution, please contact our sales team through the website or by phone, providing your specific requirements.
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