Tetramethyl tBuXPhos
Tetramethyl tBuXPhos (CAS: 857356-94-6) is a phosphine ligand with the molecular formula C33H53P and a molecular weight of 480.75 g/mol. It is primarily utilised as a key component in palladium-catalysed cross-coupling reactions, particularly for the amidation of aryl chlorides. This compound is supplied by Tech Serve Solutions at a 96% assay, suitable for research and synthesis applications.
- IUPAC
- 2-Di-tert-butylphosphino-3,4,5,6-tetramethyl-2′,4′,6′-triisopropyl-1,1′-biphenyl,Me4-t-ButylXphos,Tetramethyl di-tBuXPhos
Palladium-Catalysed Amidation
Tetramethyl tBuXPhos serves as an essential ligand in palladium-catalysed amidation reactions. It is highly effective in coupling aryl chlorides with amines, facilitating the formation of carbon-nitrogen bonds.
Buchwald-Hartwig Cross-Coupling
This phosphine ligand is a valuable tool for Buchwald-Hartwig amination and other related C-X bond formation reactions. Its specific structure promotes efficient catalytic cycles in complex organic synthesis.
Chemical Synthesis
As a specialised reagent, Tetramethyl tBuXPhos finds application in advanced organic synthesis, enabling challenging transformations where traditional methods may be insufficient. It supports the development of new chemical entities and materials.
| Molecular weight | 480.75 |
|---|---|
| Empirical formula | C33H53P |
| Assay | 96% |
| Application | Ligand used in a palladium-catalyzed amidation of aryl chlorides.1 |
| Melting point | 168-172 °C |
| Ligand For | Buchwald-Hartwig Cross Coupling ReactionC-X Bond Formation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethyl tBuXPhos used for?
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Tetramethyl tBuXPhos is primarily used as a ligand in palladium-catalyzed cross-coupling reactions, notably for the amidation of aryl chlorides and Buchwald-Hartwig amination, facilitating C-N bond formation.
What are the CAS number and formula for Tetramethyl tBuXPhos?
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The CAS number for Tetramethyl tBuXPhos is 857356-94-6, and its empirical formula (Hill notation) is C33H53P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethyl tBuXPhos with an assay of 96%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Tetramethyl tBuXPhos be handled and stored?
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Tetramethyl tBuXPhos is classified under WGK 2 in Germany. Handle with appropriate personal protective equipment in a well-ventilated area. Store in a cool, dry place away from incompatible materials.
How is Tetramethyl tBuXPhos packed, shipped, and exported?
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Tetramethyl tBuXPhos is carefully packaged to maintain its integrity during transit. As an experienced global supplier, TSS ensures compliance with all relevant regulations for the international shipment and export of chemicals.
How can I request a sample or quote for Tetramethyl tBuXPhos?
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To request a sample or a quotation for Tetramethyl tBuXPhos, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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