Tetraethylammonium fluoride hydrate
Tetraethylammonium fluoride hydrate (CAS: 98330-04-2) is a chemical compound supplied by TSS. With a molecular weight of 149.25 g/mol on an anhydrous basis, it is an essential reagent in various chemical synthesis applications. Its utility extends to roles as a deprotecting agent, a source of fluoride ions, and in protection and derivatization reactions. This compound is crucial for researchers and chemists requiring reliable fluoride delivery in organic synthesis.

Chemical Synthesis
Tetraethylammonium fluoride hydrate serves as a versatile reagent in organic synthesis. It is employed in various reactions where a soluble fluoride source is required, facilitating transformations such as nucleophilic substitutions and eliminations.
Deprotecting Agent
This compound is utilized for the selective cleavage of protecting groups in complex organic molecules. Its fluoride anion can efficiently remove silyl-based protecting groups commonly encountered in multi-step synthesis pathways.
Fluoride Source
As a readily available source of fluoride ions, Tetraethylammonium fluoride hydrate is instrumental in reactions requiring fluoride incorporation. This includes applications in fluorination reactions and the synthesis of organofluorine compounds.
Protection and Derivatization
It can be employed in derivatization strategies to introduce specific functional groups or modify existing ones. This is particularly useful in analytical chemistry and the preparation of specialized compounds.
| Molecular weight | 149.25 (anhydrous basis) |
|---|---|
| Linear formula | (C2H5)4NF·xH2O |
| Assay | 98% |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 22-26-28-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetraethylammonium fluoride hydrate used for?
+
Tetraethylammonium fluoride hydrate is used in chemical synthesis, as a deprotecting reagent, a fluoride source, and in protection and derivatization reactions.
What is the CAS number and formula for Tetraethylammonium fluoride hydrate?
+
The CAS number is 98330-04-2. The linear formula is (C2H5)4NF·xH2O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Tetraethylammonium fluoride hydrate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Tetraethylammonium fluoride hydrate?
+
This compound is a warning hazard, harmful if swallowed, inhaled, or in contact with skin, and causes skin and eye irritation. Use a dust mask type N95 (US), wear eyeshields and gloves. Handle in a well-ventilated area.
How is Tetraethylammonium fluoride hydrate packed and shipped?
+
Tetraethylammonium fluoride hydrate is packed and shipped according to international regulations for hazardous chemicals. TSS is a specialist global supplier and exporter.
How can I request a sample or quote for Tetraethylammonium fluoride hydrate?
+
To request a sample or quote for Tetraethylammonium fluoride hydrate, please contact the TSS sales team via our website or by calling our customer service line.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis