Tetradecyl-β-D-maltoside
Tetradecyl-β-D-maltoside (CAS: 18449-82-6), with the molecular formula C26H50O11, is a non-ionic detergent widely employed in biochemical research. Its amphipathic nature allows it to solubilise membrane proteins and other hydrophobic molecules, facilitating their study and purification. This compound is particularly useful in isolating and characterising protein complexes while maintaining their native structure and function, making it a valuable reagent for cell biology and biophysical investigations.
- IUPAC
- n-Tetradecyl β-D-maltopyranoside
Protein Solubilisation and Extraction
Tetradecyl-β-D-maltoside is highly effective for solubilising integral membrane proteins from biological membranes. It helps to extract and stabilise these proteins, allowing for subsequent biochemical analysis and purification.
Biochemical Assays
This non-ionic detergent is used in various biochemical assays, including enzyme activity studies and protein-ligand binding experiments. Its mild properties minimise interference with protein function.
Chromatography Applications
It serves as a detergent additive in chromatographic techniques, such as size-exclusion chromatography or ion-exchange chromatography, to maintain protein solubility and stability during separation processes.
Cryo-Electron Microscopy (Cryo-EM)
Tetradecyl-β-D-maltoside is frequently utilised in sample preparation for Cryo-EM, aiding in the solubilisation and stabilisation of membrane proteins for high-resolution structural studies.
| Molecular weight | 538.67 |
|---|---|
| Empirical formula | C26H50O11 |
| Assay | ≥99.0% (TLC) |
| Solubility | H2O: soluble10 mg/mL, clear, colorless |
| Description | non-ionic |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetradecyl-β-D-maltoside used for?
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Tetradecyl-β-D-maltoside is primarily used as a non-ionic detergent for solubilising membrane proteins, in biochemical assays, chromatography, and sample preparation for Cryo-EM.
What are the CAS number and formula for Tetradecyl-β-D-maltoside?
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The CAS number is 18449-82-6 and the empirical formula is C26H50O11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetradecyl-β-D-maltoside with an assay of ≥99.0% (TLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling Tetradecyl-β-D-maltoside?
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According to the WGK Germany classification, this substance is rated as 3, indicating a hazard to water. Appropriate handling precautions should be taken to prevent environmental release.
How is Tetradecyl-β-D-maltoside packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant regulations for safe transit and international trade.
How can I request a sample or quote for Tetradecyl-β-D-maltoside?
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Please contact our sales department via the website or direct email to request a sample or obtain a quotation.
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