Tetrabutylphosphonium chloride
Tetrabutylphosphonium chloride (CAS: 2304-30-5) is a quaternary phosphonium salt with the linear formula (CH3CH2CH2CH2)4P(Cl). This compound, with a molecular weight of 294.88 g/mol, is primarily utilised as a phase transfer catalyst and in general chemical synthesis. Its characteristics make it a valuable reagent for facilitating reactions between immiscible phases, enhancing reaction rates and yields in various organic transformations.

Phase Transfer Catalysis
Tetrabutylphosphonium chloride functions effectively as a phase transfer catalyst (PTC). It aids in transferring ionic reactants from an aqueous phase to an organic phase, or vice versa, thereby accelerating reactions that would otherwise occur slowly or not at all due to poor miscibility.
Chemical Synthesis Reagent
This phosphonium salt serves as a versatile reagent in organic synthesis. It can be employed in a variety of reactions, including nucleophilic substitutions and polymerisation processes, where its cationic nature facilitates the desired chemical transformations.
Electrolyte Component
In certain electrochemical applications, phosphonium salts like tetrabutylphosphonium chloride can be investigated for use as components in electrolytes, contributing to ionic conductivity.
| Molecular weight | 294.88 |
|---|---|
| Linear formula | (CH3CH2CH2CH2)4P(Cl) |
| Assay | 96% |
| Melting point | 62-66 °C (dec.)(lit.) |


Hazard statements
- H302Harmful if swallowed
- H310Fatal in contact with skin
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2928 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrabutylphosphonium chloride used for?
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Tetrabutylphosphonium chloride (CAS: 2304-30-5) is primarily used as a phase transfer catalyst and a reagent in chemical synthesis, particularly in organic transformations.
What is the CAS number and formula for Tetrabutylphosphonium chloride?
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The CAS number for Tetrabutylphosphonium chloride is 2304-30-5, and its linear formula is (CH3CH2CH2CH2)4P(Cl).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrabutylphosphonium chloride with an assay of 96%. This product is supplied for research and general chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Tetrabutylphosphonium chloride be handled safely?
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Tetrabutylphosphonium chloride is a Danger substance (GHS05, GHS06) and is harmful if swallowed, toxic in contact with skin, causes severe skin burns and eye damage, and is fatal if inhaled. Appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection, must be used. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is Tetrabutylphosphonium chloride a controlled substance?
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The provided data does not indicate that Tetrabutylphosphonium chloride is a controlled substance.
How is Tetrabutylphosphonium chloride packed and shipped?
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Tetrabutylphosphonium chloride is classified under UN 2928, Hazard Class 6.1, Packing Group II for transport. Specific packaging and shipping procedures adhere to relevant dangerous goods regulations for international export. Please contact us for detailed shipping information.
How can I request a sample or quote for Tetrabutylphosphonium chloride?
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To request a sample or a quote for Tetrabutylphosphonium chloride, please contact the Tech Serve Solutions sales department via our website or by phone, providing your contact details and the quantity required.
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