Tetrabutylammonium hydroxide solution
Tetrabutylammonium hydroxide solution (CAS: 2052-49-5), with the linear formula (CH3CH2CH2CH2)4N(OH) and a molar mass of 259.47 g/mol, is a strong organic base. Supplied as a 1.0 M solution in water, it is frequently utilised as a phase-transfer catalyst in organic synthesis. Its ACS reagent grade ensures suitability for demanding analytical and synthetic laboratory applications.

Phase-Transfer Catalyst
Tetrabutylammonium hydroxide acts as an effective phase-transfer catalyst, facilitating reactions between reactants in immiscible phases. This enhances reaction rates and allows for milder reaction conditions in organic synthesis.
Organic Synthesis Reagent
As a strong organic base, it is employed in various organic transformations, including deprotonation reactions and as a counter-ion in ionic reactions. Its solubility in organic solvents makes it a versatile reagent.
Analytical Chemistry
This compound serves as a reagent in analytical chemistry, particularly in titration applications. Its well-defined concentration as an ACS reagent grade makes it suitable for accurate quantitative analysis.
| Molecular weight | 259.47 |
|---|---|
| Linear formula | (CH3CH2CH2CH2)4N(OH) |
| Assay | 1.0 M±0.02 M (ACS specification) |
| Grade | ACS reagent |
| Colour | APHA: ≤30 |
| Density | 1 g/mL at 25 °C |
| Refractive index | n20/D 1.389 |
| Concentration | 1.0 M in H2O |
| Impurities tested | ≤0.2% tributylamine |
| Application | Phase-transfer catalyst.1 |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3267 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
| Cation traces | K: ≤2 ppmNa: ≤2 ppm |
| Anion traces | carbonate (CO32-): ≤0.1%chloride (Cl-): ≤0.08% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetrabutylammonium hydroxide solution used for?
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Tetrabutylammonium hydroxide solution (CAS: 2052-49-5) is primarily used as a phase-transfer catalyst in organic synthesis and as a strong organic base in various chemical reactions. It also finds application in analytical chemistry, including titration.
What are the CAS number and formula for Tetrabutylammonium hydroxide solution?
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The CAS number for Tetrabutylammonium hydroxide solution is 2052-49-5. Its linear formula is (CH3CH2CH2CH2)4N(OH).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetrabutylammonium hydroxide solution in ACS reagent grade, with an assay of 1.0 M ± 0.02 M in water. We do not represent this product as USP, BP, or EP grade.
How should Tetrabutylammonium hydroxide solution be handled safely?
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Tetrabutylammonium hydroxide solution is corrosive and can cause severe skin burns and eye damage (H314). Always wear appropriate personal protective equipment, including gloves, goggles, and face shields. Handle in a well-ventilated area and consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Is Tetrabutylammonium hydroxide solution shipped or exported by TSS?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including Tetrabutylammonium hydroxide solution.
How can I request a quote or sample?
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To request a quote or a sample of Tetrabutylammonium hydroxide solution, please contact our sales team through the website or by phone.
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