tert-Butyl carbazate
Tert-Butyl carbazate (CAS 870-46-2) is a valuable organic compound with the linear formula (CH3)3COCONHNH2 and a molecular weight of 132.16 g/mol. This white to off-white solid serves as a key reagent in chemical synthesis and peptide chemistry. Its primary function is as a protecting group for amines, facilitating controlled reactions in complex molecular constructions. It is widely employed in the development of pharmaceuticals and in chemical biology research.
- IUPAC
- tert-Butoxycarbonyl hydrazide,Boc-hydrazide
- Synonyms
- tert-Butoxycarbonyl hydrazideBoc-hydrazide
Amine Protection in Organic Synthesis
Tert-Butyl carbazate is utilized to introduce the tert-butoxycarbonyl (Boc) protecting group onto amine functionalities. This protection strategy is crucial for preventing unwanted side reactions during multi-step syntheses, particularly in the preparation of complex organic molecules and pharmaceutical intermediates.
Peptide Synthesis Reagent
In peptide chemistry, tert-Butyl carbazate is employed as a building block or derivatizing agent. It allows for the selective modification and protection of amino groups within peptide chains, enabling the controlled assembly of peptides with specific sequences and properties.
Chemical Biology Research
This compound finds application in chemical biology for modifying biomolecules or in the synthesis of probes and labelled compounds. Its ability to selectively react with amines makes it a useful tool for investigating biological processes at the molecular level.
| Molecular weight | 132.16 |
|---|---|
| Linear formula | (CH3)3COCONHNH2 |
| Assay | 98% |
| Grade | purum |
| Boiling point | 63-65 °C/0.1 mmHg(lit.) |
| Melting point | 39-42 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tert-Butyl carbazate used for?
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Tert-Butyl carbazate is primarily used as a reagent for amine protection in organic synthesis and peptide chemistry, and in chemical biology research for derivatization and modification of biomolecules.
What is the CAS number and formula for Tert-Butyl carbazate?
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The CAS number for Tert-Butyl carbazate is 870-46-2, and its linear formula is (CH3)3COCONHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tert-Butyl carbazate with a minimum assay of 98% in 'purum' grade. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Tert-Butyl carbazate be handled safely?
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Tert-Butyl carbazate is combustible. When handling, wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Avoid exposure to heat, sparks, and open flames.
How is Tert-Butyl carbazate packed and shipped?
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Tech Serve Solutions offers Tert-Butyl carbazate in various pack sizes suitable for laboratory and industrial use. We are experienced in exporting fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample of Tert-Butyl carbazate?
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To request a quote or a sample of Tert-Butyl carbazate, please contact our sales team through the website or by phone, providing your specific requirements.
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